نتایج جستجو برای: thalassemia carrier rate
تعداد نتایج: 1042539 فیلتر نتایج به سال:
Abstract Background: Patients with Thalassemia Major suffer from different skeletal deformities. This study was carried out to compare the rate of deformities between patients with Major and minor thalassemia. Materials and Methods: This historical cohort study was done on 87 patients with major thalassemia (case group) and 87 patients with minor thalassemia (control group). Indices of skel...
OBJECTIVE Thalassemia is a common disease in many countries, in which several complications such as infections can occur. Although aberration in the function of the immune system could be a reason for such complication, a little is known about the status of humoral immune system in major beta thalassemia. In this study we measured serum immunoglobulins level in a group of patients with major be...
This retrospective study aimed to describe the magnitude of false positive screening for thalassemia in a primary care setting of Thailand. The study was conducted from 1999 to 2008 and analyzed 13,745 positive cases. It involved a combination of one tube osmotic fragility (OF) and dichlorophenol indophenol (DCIP) precipitation tests. The number of cases increased over the ten-year period, corr...
Thalassemia and hemoglobin E (Hb E) are common in Thailand. Individuals with thalassemia trait usually have a normal hemoglobin concentration or mild anemia. Therefore, thalassemic individuals who have minimum acceptable Hb level may be accepted as blood donors. This study was aimed at determining the frequency of α-thalassemia 1 trait, β-thalassemia trait, and Hb E-related syndromes in Souther...
We evaluated the combination of two indices of red blood cell count (RBC) and red blood cell distribution with index (RDWI) and extrapolated HbA2 values in differential diagnosis of iron deficiency anemia (IDA) and beta-thalassemia traits (BTT) associated with IDA. A total 129 subjects were included in this study. RBC/RDWI was able to diagnose 32% beta-thalassemia with iron deficiency while 66%...
Background and Aim: Thalassemia is considered as the most important monogenic disorders around the world. So far, about 60 mutations of this type have been reported in Iranian patients. Comparison between different provinces of the country reveals that the dispersion of the mutations is significantly various with respect to their types and frequencies. The current study aimed at assessing preva...
Background: Pain during invasive procedures is an unpleasant thing experienced by all children when hospitalized, including with acute illnesses or chronic diseases such as thalassemia. Nurses need to implement interventions from atraumatic care reduce the pain felt children, providing audiovisual distraction techniques. This study aimed see difference in thalassemia and non-thalassemia after b...
Background: In recent years, the success in management of thalassemic patients, has allowed for some previously unrecognized complications including renal abnormalities to emerge. This prospective study aimed to investigate kidney iron overload by means of MRI T2* and also renal function based on laboratory tests for early markers of glomerular and tubular dysfunction among adult Iranian transf...
By WOLF W. ZUELZER, ABNER R. ROBINSON AND CLIFFORD R. Booian T HE EXISTENCE of more than one kind of gene capable of producing the stigmata of thalassemia was first suggested’ as a possible explanation for the surprisingly wide spectrum of hematologic phenotypes observed in syndromes thought to result from the combination of a gene for thalassemia with a gene for one of the abnormal hemoglobins...
OBJECTIVE The Turkish Society of Pediatric Hematology set up a National Hemoglobinopathy Registry to demonstrate the demographic and disease characteristics of patients and assess the efficacy of a hemoglobinopathy control program (HCP) over 10 years in Turkey. MATERIALS AND METHODS A total of 2046 patients from 27 thalassemia centers were registered, of which 1988 were eligible for analysis....
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