introduction low dose rate brachytherapy sources have been widely used for interstitial implants in tumor sites, particularly in prostate. dosimetric characteristics of a new irseed 125i brachytherapy source have been determined using the lif thermoluminescent dosimeter (tld) chips. materials and methods dose rate constant, radial dose function, and anisotropy function around the irseed 125i so...

The aim of this study was to investigate the pharmacokinetics of thiamphenicol glycinate (TG) and thiamphenicol (TAP) after intravenous (i.v.) infusion of TG hydrochloride in healthy Chinese by evaluating the pharmacokinetic parameters, to provide clinical guidance in TG application. In this double-blinded, phase I clinical trial, 24 healthy Chinese volunteers were recruited and divided into th...

BACKGROUND To establish the feasibility of the dosimetric compliance criteria of the RTOG 1308 trial through testing against Intensity Modulation Radiation Therapy (IMRT) and Passive Scattering Proton Therapy (PSPT) plans. METHODS Twenty-six lung IMRT and 26 proton PSPT plans were included in the study. Dose Volume Histograms (DVHs) for targets and normal structures were analyzed. The quality...

Background: Electronic portal imaging devices (EPIDs) play an important role in radiation therapy portal imaging, geometric and dosimetric verifications. A successful utilization of EPIDs for imaging and dosimetric purposes requires a reliable quality control process routine to be carried out regularly. In this study, two in-house phantoms were developed and analyzed for implementation in a qua...

In this work, we report a comprehensive quality assurance (QA) process for the commissioning of an Electronic Brachytherapy (EB) system at one of the first U.S. sites to apply the device clinically. Thus far, EB systems have been released only for intracavitary breast treatments. As such, EB as an Accelerated Partial Breast Irradiation (APBI) treatment modality is relatively unstudied and is un...

In low energy brachytherapy, the presence of tissue heterogeneities contributes significantly to the discrepancies observed between treatment plan and delivered dose. In this work, we present a simplified analytical dose calculation algorithm for heterogeneous tissue. We compare it with Monte Carlo computations and assess its suitability for integration in clinical treatment planning systems. T...

The proposed two types of multi-valued D flip-flops are NMAX-TG D flip-flop and NMIN-TG D flip-flop A NMAX-TG D flip-flop and a NMIN D flip-flop are composed of the components such as NMAX D flip-flops, NMIN D flip-flops and T-gate circuits. In the simulations, sampling frequencies of NMAX-TG D flip-flop and NMIN-TG D flip-flop are measured around 500 kHz and 1 MHz, respectively. The PDP parame...

Introduction: The use of long-half-life Cobalt source instead of iridium source will be very helpful in HDR brachytherapy for treatment of cervical cancer. The aim of this study was compared the treatment time with cobalt and iridium source in brachytherapy for treatment of cervical cancer using Tandem-ovoid applicator. Materials and Methods: In this study, 19...