Background: It is still controversial that the stem cells isolated from human dental pulp meets the criteria for mesenchymal stem cells (MSCs). The aim of the present study was to examine whether or not they are MSCs, or are distinct stem cells population residing in tooth pulp. Methods: Adherent fibroblastic cells in the culture of pulp tissue from human third molars were propagated through se...

Abstract Glioblastoma is the most common malignant brain tumor. Unfortunately, outcomes for this cancer are poor. Even with standard of care treatment, median survival time only 15 months and disease almost universally lethal. Therefore, more effective therapies urgently needed to treat condition. One promising treatment chimeric antigen receptor (CAR) T cell therapy. CAR cells white blood that...

background: it is still controversial that the stem cells isolated from human dental pulp meets the criteria for mesenchymal stem cells (mscs). the aim of the present study was to examine whether or not they are mscs, or are distinct stem cells population residing in tooth pulp.   methods: adherent fibroblastic cells in the culture of pulp tissue from human third molars were propagated through ...

The fate of cell surface tumor-associated antigens shed by viable human melanoma cells was studied in vitro. Labeled surface material shed by radio-iodinated melanoma cells was incubated with a variety of unlabeled human cells for 24 hr. Both melanoma-associated antigens (MAAs), quantitated by specific immunoprecipitation, and unrelated surface macromolecules were degraded or inactivated by nor...

The fate of cell surface tumor-associated antigens shed by viable human melanoma cells was studied in vitro. Labeled surface material shed by radio-iodinated melanoma cells was incubated with a variety of unlabeled human cells for 24 hr. Both melanoma-associated antigens (MAAs), quantitated by specific immunoprecipitation, and unrelated surface macromolecules were degraded or inactivated by nor...

BACKGROUND Miltefosine, an anti-cancer drug that has been successfully repositioned for treatment of Leishmania infections, has recently also shown promising effects against Schistosoma spp targeting all life cycle stages of the parasite. The current study examined the effect of treating Schistosoma mansoni adult worms with miltefosine on exposure of worm surface antigens in vitro. METHODOLOG...

The temperature data from 3 meteorological stations (Kashi, Ruoqiang, and Hotan) in the South of Tarim River Basin (STRB) during 1964-2011 were analyzed by Mann-Kendall test and correlation analysis. The results from Mann-Kendall test show that the surface temperature (ST), 850 hPa temperature (T850), and 700 hPa temperature (T700) exhibited upward trends, while 300 hPa temperature (T300) revea...

Pollutants (ASEPs) To Better Understand their Environmental Cycling and Planetary Boundaries Judith A. Perlinger,*,† Hugh S. Gorman, ‡ Emma S. Norman, Daniel Obrist, Noelle E. Selin, Noel R. Urban,† and Shiliang Wu#,† †Department of Civil & Environmental Engineering, Michigan Technological University, Houghton, Michigan 49931, United States ‡Department of Social Sciences, Michigan Technological...