BACKGROUND Breast reduction is one of the most commonly performed plastic surgery procedures. Many approaches to breast reduction have been described, including inverted-T and vertical scar techniques and various types of dermoglandular pedicle for the nipple. OBJECTIVE This study compares the outcomes of patients undergoing vertical scar medial pedicle versus inferior pedicle inverted-T scar...

Scarring is the body’s natural response to a wound. Yet, this healing process can create significant functional and cosmetic problems. It impacts daily life and can create issues in self-esteem. Traditionally, the treatment of scars has been surgical. Despite meticulous surgical technique, scars still form. Revision may be in the form of excising the scar to create a “thinner” line, or the surg...

BACKGROUND Recent studies have suggested that Bacille Calmette-Guerin (BCG) vaccination may have a non-specific beneficial effect on infant survival and that a BCG scar may be associated with lower child mortality. No study has previously examined the influence of BCG vaccination on cause of death. METHODS Two cohorts (A and B) were used to describe the mortality pattern for children with and...

The Burn Scar Index, often called the Vancouver Scar Scale, is widely used in clinical practice and research to document change in scar appearance. Several sections of the Index require equipment to accurately score the items. Additionally, the numeric scores are difficult to remember. We recently devised a pocket-sized tool to aid in scoring the scar and to increase staff compliance in use of ...

BACKGROUND The Bacillus Calmette-Guérin vaccine (BCG) against tuberculosis is administered intradermally, and vaccination is often followed by a scar at the injection site. Among BCG-vaccinated individuals, having a scar has been associated with lower mortality. We aimed to examine the impact of vaccination technique for scarring in a high income setting, by assessing the associations between t...

Each year in Hong Kong, about 350,000 surgical procedures are conducted for various types of conditions. Previous review indicated that the prevalence of hypertrophic scar among Caucasians ranged from 15% to 63% and that the incidence was even higher among non-Caucasians. This study aims to find out the prevalence rate of hypertrophic scar among the Hong Kong Chinese population after standardiz...

OBJECTIVES To critically assess the prevalence among schoolchildren 6 to 9 years of age throughout the Dominican Republic of a bacille Calmette-Guérin (BCG) vaccination scar, and to examine the relationship between nutritional and sociodemographic factors and the likelihood of having a BCG scar. METHODS This correlational study used the database of the Second National Census on Height and Wei...

BACKGROUND Defining the arrhythmogenic substrate is essential for successful ablation of scar-related ventricular tachycardia. The visual characteristics of endocardial ischemic scar have not been described in vivo. The goal of this study was (1) to quantify the visual characteristics of normal tissue, scar border zone, and dense scar in vivo with the use of a novel endoscopic catheter that all...

BACKGROUND Abnormal scar development following burn injury can cause substantial physical and psychological distress to children and their families. Common burn scar prevention and management techniques include silicone therapy, pressure garment therapy, or a combination of both. Currently, no definitive, high-quality evidence is available for the effectiveness of topical silicone gel or pressu...

Cardiac fibrosis is a serious condition currently lacking effective treatments. It occurs as a result of cardiac fibroblast (CFB) activation and differentiation into myofibroblasts, characterized by proliferation, extracellular matrix (ECM) production and stiffening, and contraction due to the expression of smooth muscle α-actin. The mechanical properties of myocardium change regionally and ove...