We report a case of a 58-year-old male without any comorbidities who was thrombolysed with streptokinase for acute anterior wall myocardial infarction and developed massive hemoptysis with dyspnea and imaging features showing bilateral alveolar infiltrates. He was diagnosed with pulmonary alveolar hemorrhage and treated conservatively. His condition improved, and follow-up imaging showed resolu...

BACKGROUND Thrombus formed in blood vessels lead to atherothrombotic diseases such as myocardial or cerebral infarction. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs sometimes cause serious and fatal consequences. Herbal preparations have been used since ancient times for the treatment of several diseases although they show little ...

a 45- year old man with a history of aortic valve replacement presented with acute chest pain which was diagnosed to be anterior wall myocardial infarction. he received thrombolytic therapy with streptokinase. echocardiography and fluoroscopy showed normally functioning ball and cage aortic prosthesis. coronary arteriography showed globular filling defect in midportion of left anterior descendi...

Thrombolytic therapy, which involves the administration of agents designed to increase fibrinolytic capacity, has been utilized in respiratory medicine for more than 50 years. A variety of agents have been used to effect thrombolysis, including urokinase plasminogen activator (uPA) and streptokinase. Tissue plasminogen activator (tPA) has also been used to effect thrombolysis. Both uPA and tPA ...

BACKGROUND As compared with thrombolytic therapy, primary coronary angioplasty results in a higher rate of patency of the infarct-related coronary artery, lower rates of stroke and reinfarction, and higher in-hospital or 30-day survival rates. However, the comparative long-term efficacy of these two approaches has not been carefully studied. METHODS We randomly assigned a total of 395 patient...

The natural course of acute pulmonary embolism depends primarily on whether the embolism has been detected and treated [1-4]. The haemodynamic severity of acute pulmonary embolism largely depends on the previous state of the cardiopuLmonary system in patients without any previous cardiopulmonary di ease [1, 5], the degree of haemodynamic severity (e.g. that of pulmonary hypertension) depends ex...

OBJECTIVES To compare outcomes from accelerated alteplase (recombinant tissue plasminogen activator, t-PA) and streptokinase use in acute myocardial infarction. METHODS Review of available studies identified by Medline and other literature searches that met the criteria of being a prospective, randomised clinical trial enrolling over 1000 patients with acute myocardial infarction. The studies...

W'ITithin a short time after the first report on ~ the successful cloning and expression of TV tissue-type plasminogen activator (t-PA),l several laboratories began working on creating new t-PA derivatives through site-directed mutagenesis.2-4 t-PA has unique properties that make it an attractive choice for thrombolytic therapy. t-PA is "fibrin directed"; that is, it preferentially activates th...

Background: Thrombolytic therapy in patients with sub-massive pulmonary embolism (SMPTE) needs further assessment. Objectives: The current study aimed to assess a potential benefit of thrombolytic and non-thrombolytic therapy in patients with SMPTE. Patients andMethods: One hundred-nineteen patients were enrolled with SMPTE from 2006 to 2010 in the tertiary care center of Rajaie medical and res...