While the efficacy and safety of topical 4-hydroxyanisole (mequinol) 2%/tretinoin 0.01% therapy has been established in Caucasian populations, those with skin types I-II, little research has focused on individuals with darker skin types. The purpose of this open-label study was to evaluate the efficacy and safety of mequinol 2%/tretinoin 0.01% solution in the treatment of solar lentigines in As...

tive, technical, and material support: Beach and Wilkinson. Study supervision: Khumalo. Financial Disclosure: None reported. Funding/Support: The original study was supported in part by the North American Hair Research Society (Dr Beach) and the Women’s Dermatologic Society (Dr Beach). Dr Wilkinson is supported by the Medical Research Council (United Kingdom) and performed the laboratory work i...

Ink spot lentigoは日光黒子の稀な亜型で，露光部位に多くは孤発性に生じる小型で均一な色調の黒色斑である．51歳，skin type IIIの日本人男性に生じた1例を報告する．半年前に気づいた，背部中央の長径7 ㎜，浸潤を触れない均一な色調の黒色斑であり，ダーモスコピーでは濃褐色から黒色の定型的色素ネットワークを呈した．病理では単純黒子の所見で，延長する表皮索の先端にメラニン沈着が優位に分布するskip areaがみられた．Melan-A Giemsa染色で，メラノサイトは表皮基底層で軽度個別性に増加しているが，明らかな異型性はなかった．Ink lentigoの報告は国外では20例あり，skin I〜IIの白人に多い．自験例は本邦初であるが，周知されていないためink lentigoとして報告されていない可能性がある．本疾患は，濃い黒色調のため臨床的には表在拡大型黒色腫と...

abstract: there is always a need to increase a distillate output of solar still. if plates will be used inside solar still then distillate output of solar still are expected to increase. hence, an experimental study is conducted to improve distillate output of basin solar stills by increasing the effective surface area with the help of different plates. for the purpose of experiment, three sola...

The diagnosis of pigmented actinic keratosis can be complicated in clinical practice. The differential diagnosis with lentigo maligna melanoma can be difficult due to common clinical and dermoscopic characteristics. We present 5 cases of pigmented actinic keratosis in 4 patients. The most common dermoscopic finding was a grayish-brown granulation with a perifollicular distribution, present in a...

Linear pigmentation of the nail apparatus most reflects longitudinal melanonychia. It results either from simple activation of matrical melanocytes induced by various factors or from benign (lentigo or naevus) or malignant (melanoma) melanocyte hyperplasia. Hematomas and some fungal infections can falsely resemble linear pigmentation. Non-linear pigmented lesions of the nail bed are most often ...

in recent decades, due to increasing prices of fossil fuels and environmental pollution resulting from the increased energy demand, researches on renewable energy sources have attracted lots of researcher’s attention. limited investing sources and environmental issues are important factors effecting electricity generation sector. minimizing costs and environmental damages are issues being consi...

BACKGROUND Lentigo maligna (LM) is a melanoma in situ on sun-damaged skin, with a strong predilection to the head and neck area of the elderly. Many therapeutic modalities have been proposed in the treatment of this pathology, including surgery, cryotherapy, radiotherapy and topical imiquimod. Up to date surgical excision remains the treatment of choice with the lowest recurrence rate. Recently...