a simple and efficient one-pot method for the preparation of aromatic iodides has been developed by sequential diazotization–iodination of aromatic amines employing sodium nitrite and sodium iodide in the presence of acidic ionic liquid n-methyl-2-pyrrolidonum hydrosulfate ([h-nmp]hso4). the diazonium salts that are formed by this ionic liquid are stable at room temperature and react rapidly wi...

thiopental sodium is an ultra short-acting barbiturate. due to its redistribution characteristic, its first injection has a short term effect. in order to elongate its anesthesia duration, more injections are needed. as these additional injections extend the recovery length , weaken respiration and causes other dangerous effects; its repeated use is considered unsafe. citicoline is a natural su...

Levels of sodium pump and of sodium channels were measured at different stages of membrane purification. Microsomal fractions of normal human muscle have maximal binding capacities for tetrodotoxin of 230 fmol/mg of protein and of 7.4 pmol/mg of protein for ouabain. Dissociation constant for the complexes formed by the tetrodotoxin derivative and by ouabain with their respective receptors were ...

migraine is a common and incapacitating neurologic disorder manifesting with episodic moderate to a severe headache and other symptoms such as photophobia, phonophobia, nausea, and vomiting. triptans and ergot compounds have been used as treatment options for an acute migraine headache for many years. triptans are considered the first line of treatment in patients with moderate to a severe migr...

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim (1 of 9) 1600100 wileyonlinelibrary.com 10–20 d (compared to 120 d in patients without the disease), resulting in a low RBC count and low level of hemoglobin (anemia).[4] Deoxygenation results in HbS polymerization and RBC shape change to the rheologically unfavorable sickle form that can inhibit blood flow and cause organ damage, stroke, infect...

Ginger (Zingiber officinale Roscoe) rhizomes are mostly used as spice and medicine due to their high aroma intensity medicinal bioactive compounds. However, the volatile compounds of ginger, partly responsible for its properties, can be affected by pretreatment, drying method, extraction processes employed. The objective this study was assess effects pretreatment on yellow ginger variety at nin...

background and aims. this in vitro study evaluated the effect of delaying composite resin restorative procedures bonded with total-etch and self-etch adhesive systems on microleakage following root canal irrigation with sodium hypochlorite (naocl) solution. materials and methods. the roofs of pulp chambers and roots (1–2 mm below furcation) of 40 human first molar teeth were cut and pulp tissue...

to assess the effects of different final irrigants on the bond strength of bonded root filling materials, epiphany/resilon and epiphany self-etch (se)/resilon.the root canals of eighty single-rooted extracted human teeth were prepared. after the smear layer was removed using 17% edta, the samples were randomly divided into eight groups. in groups 1 and 2, no additional irrigant was used after e...

The decarboxylation of racemic threo and erythro-3,4-dihydroxyphenylserine (DOPS), norepinephrine (NE) precursors, has been reported in mammalian peripheral and central nervous system tissues in vivo (1-5). It has also been demonstrated both in vitro and in vivo that the rate of racemic erythro-DOPS decarboxylation is more rapid than that of racemic threo-DOPS (6). A recent report on the action...