Accessory, supernumerary, or-most simply-B chromosomes, are found in many eukaryotic karyotypes. These small chromosomes do not follow the usual pattern of segregation, but rather are transmitted in a higher than expected frequency. As increasingly being demonstrated by next-generation sequencing (NGS), their structure comprises fragments of standard (A) chromosomes, although in some plant spec...

a study was conducted to identify ssr markers linked to leaf rust resistance genes lr24 and lr28 and to be used for marker-assisted selection (mas) to transfer both genes to a widely cultivated wheat variety mp 3299 under rainfed condition. f2 individuals of the cross mp 3299×nil pbw 343 were used for generating genotypic data employing closely linked scar markers s73719 and s421570 to lr24 and...

Low-grade fibromyxoid sarcoma (LGFMS) is a rare, low-grade malignant soft tissue tumor that is often mistaken for either benign or more malignant tumor types. Commonly, this tumor affects young adults and typically arises in the deep proximal extremities or trunk with frequent recurrences and can metastasize to the lungs many years later. Most cases have a recurrent balanced translocation invol...

BACKGROUND Tetrasomy 18p is a very rare chromosomal disorder and is the result of a spontaneous mutation early in embryonic development in most of the cases. This condition is characterised by the presence of a supernumerary 18p isochromosome (i(18p)) in all or some cells of the affected individual. It has a prevalence of 1/180000 live births and affects both genders equally. MATERIALS AND ME...

High resolution comparative genomic hybridisation (HR-CGH) is a diagnostic tool in our clinical cytogenetics laboratory. The present survey reports the results of 253 clinical cases in which 47 abnormalities were detected. Among 144 dysmorphic and mentally retarded subjects with a normal conventional karyotype, 15 (10%) had small deletions or duplications, of which 11 were interstitial. In addi...

Thosen (Amer. J. phys. Anthrop., [n.s. 10:155, 1952) listed dominant, irregular donsinant, recessive, and sex-linked genes as the explanation for hypodontia. Grahnhn (Odont. Revy, 7, Sup)pl. 3, 1956) concluded from studies of Swedish families that dominant genes were involved in the majority of cases of hypodontia and that probably a number of genetic entities were associated with its occurrenc...

Phylloid hypomelanosis is a distinct type of pigmentary mosaicism characterized by congenital hypochromic macules resembling a floral ornament with various elements such as round or oval patches, asymmetrical macules similar to begonia leaves, or oblong lesions. It has been found to be predominantly associated with abnormalities in chromosome 13 and sometimes as-sociated with different extracut...