Submit Manuscript | http://medcraveonline.com MOJ Toxicol (2016), 2(1): 00026 Abbreviations: RPM: Revolutions Per Minute; AST: Serum Aspartate Aminotransferase; ALT: Serum Glutamate Pyruvate Transaminase; Scr: Serum Creatinine; BUN: Blood Urea Nitrogen; C: Control; V: Venom; VC : Vitamin; VVC: Venom+Vitamin C ; TBS :Tris Buffered Saline; SOD: Superoxide Dismutase; Cat: Catalase; GSH-Px: Glutath...

Background: There is substantial evidence that environmental factors cause or accelerate the onset of malignancy. Environmental factors, due to the presence of many pollutants and carcinogenic agents, alter cellular growth, which leads to biochemical changes in the blood. Materials and Methods: In the present study, we estimated serum pseudocholinesterase (PCHE), serum aspartate transaminase (A...

Nonalcoholic fatty liver disease has been suggested to be associated with alanine aminotransferase (ALT) elevation in hepatitis B virus (HBV)-infected patients with HBe antigen (HBeAg)-negativity and a low HBV-DNA level. However, few studies have evaluated the association according to histological findings of the liver.Among a total of 198 HBV-infected patients who received a percutaneous liver...

OBJECTIVE Fe is an essential element for erythropoiesis and Hb synthesis. High Hb levels affect the blood's viscosity and are associated with cardiovascular dysfunction. The aim of the present study was to examine relationships of Hb and cardiometabolic abnormalities with the risk of alanine aminotransferase (ALT) elevation in adolescents. DESIGN A population-based, cross-sectional study. S...

Because elevation of serum alanine aminotransferase (ALT) levels plays an important role in developing of type 2 diabetes (T2D),1 we evaluated whether the elevated ALT levels are associated with incident impaired fasting glucose (IFG) and T2D, in obese women. Obese (body mass index [BMI] ≥ 30 kg/m2) nonpregnant women aged 20 to 65 years were enrolled in a cross-sectional study. Alcohol consumpt...

Nonalcoholic fatty liver disease (NAFLD) is no longer considered to be a normal physiologic condition without any clinical significance. It is now widely accepted that nonalcoholic steatohepatitis (NASH), a type of fatty liver disease, can progress to end-stage liver disease and increase the risk of mortality. In addition, NAFLD patients are associated with a significantly higher overall mortal...

The study aimed to investigate the diagnostic value of liver function enzymes in patients with choledocholithiasis. The retrospective study included 120 choledocholithiasis patients (experimental group), 110 cholecystolithiasis patients (control group) and 60 healthy subjects (healthy group) from January 2013 to December 2014. Blood sample was extracted from each participant, and biochemical te...

We studied the interaction between paracetamol (acetaminophen U.S.P.) and enflurane. Sixteen rats were assigned to four groups (n = 4) to receive: paracetamol 7.5 mg/100 g body weight; paracetamol plus 1% enflurane; 1% enflurane alone, or no treatment (controls). Animals were killed 6 h later. A second series of 16 were treated identically, but were killed after 24 h. Measurements were made of ...

AIM to assess the safety and efficacy of telbivudine therapy in adult patients with CHB in Indonesia. METHODS the study design was prospective cohort study. Multicenter study of adult CHB patients requiring oral antiviral therapy in daily practice setting. All patients received 600 mg of telbivudine daily for one year. Recruitment and decision to start telbivudine therapy was based on clinica...