Recent studies suggest that subjects with hypothyroidism under therapy with levothyroxine (L-T4) might develop oxidative stress. The aim of this study was to test a redox-balance modulator, fermented papaya-based nutraceutical (FPP), together with subclinical (SH) or mild hypothyroidism (MH) treatment in view of biochemical changes. A total of 60 females treated for SH-MH were divided into two ...

BACKGROUND In the last two years several cases of severe contact dermatitis related to newly acquired sofas and armchairs originating from China have been published. The responsible allergen is dimethylfumarate (DMF), an extremely potent sensitizer and irritant found in sachets inside the furniture. Recently, cases of contact dermatitis related to shoes and riding helmets have also been describ...

A rapid and sensitive RP-HPLC method with UV detection (323 nm) for routine analysis of strontium ranelate in bulk and in pharmaceutical formulation as sachet was developed. Chromatography was performed with mobile phase containing a mixture of monobasic potassium phosphate buffer and methanol (3:1 v/v) with the flow rate of 0.8 ml/min at 25 o C. In the range of 50-250 μg/ml, the linearity of s...

The aim of the evaluation was to establish bioequivalence between two oral 3.0 g sachet forms of L-ornithine-L-aspartate (LOLA). It was designed as randomised, two-way crossover study with a 1-week washout interval. Blood samples were collected throughout a 12 h period after administration of reference and test product to 12 fasting healthy male volunteers. Plasma were analyzed by sensitive, re...

Hutan Pelawan yang berlokasi di Desa Namang, Kabupaten Bangka Tengah, Provinsi Kepulauan Belitung memiliki potensi sangat besar sebagai hutan kehayati juga dimanfaatkan oleh masyarakat sarana wisata edukasi dan sebagainya. Salah satu andalan daya Tarik ini adalah menghisap madu secara langsung dari sarang lebah. Sayangnya, lokasi fasilitas ada sebelumnya tidak kondusif. Selain itu, produk dimil...

Nosocomial infections present a growing challenge in wound care, especially in light of the rising distribution of multiresistant bacterial strains. Because wounds are an ideal breeding ground for pathogens, special care must be taken in choosing the right dressing. Following the traditional preventive approach, exposure of the nursing staff as well as the wounds to pathogens should be reduced....