WW domain-containing transcription regulator 1 (WWTR1) is one of the primary effectors in Hippo pathway, which plays essential roles cell differentiation into trophectoderm (TE) and inner mass lineages at blastocyst stage. However, little known about WWTR1 preimplantation development. The present study aimed to explore significance expression development using an mRNA knockdown (KD) system bovi...

CLIP-170 belongs to a group of proteins (+TIPs) with the enigmatic ability to dynamically track growing microtubule plus-ends. CLIP-170 regulates microtubule dynamics in vivo and has been implicated in cargo-microtubule interactions in vivo and in vitro. Though plus-end tracking likely has intimate connections to +TIP function, little is known about the mechanism(s) by which this dynamic locali...