The necessity and importance of teaching pragmatics has come to light by many researchers (e.g. Rose & Kasper, 2001). Due to the consensus over the need to teach pragmatic competence, the main issue now centers on the question of how we should teach this competence in the most effective way. Consistent with this line of research, the present study aimed to investigate the effectiveness of deduc...

F u n d a m e n t a l p r o b l e m s of g r o w t h a n d t h e sc reen ing of c h e m o t h e r a p e u t i c a g e n t s b e c o m e m o r e n e a r l y de f inab le in precise c h e m i c a l t e r m s w h e n q u a n t i t a t i v e p rocedu re s (5, 9) for e s t i m a t ing p ro l i f e r a t i on are used in t h e p resence of a c h e m i c a l l y def ined b a c k g r o u n d m e d i u ...

I n t h i s p a p e r , w e w i l l d e s c r i b e a g e n e r a l m e t h o d o l o g y w h i c h c a n b e u t i l i z e d i n t h e g e n e r a t i o n o f i m a g e r e c o g n i t i o n b e n c h m a r k p r o b l e m s , w h i c h c a n b e u s e d t o v a l i d a t e a n d v e r i f y l e a r n i n g a l g o r i t h m s f o r d a t a s t r u c t u r e s . T h i s m e t h o d o l o g y i...

Sao Paulo Med J. 2007;125(3):132-8. O R IG IN A L A R T IC L E João Carlos Belloti João Baptista Gomes dos Santos Álvaro Nagib Atallah Walter Manna Albertoni Flavio Faloppa Fractures of the distal radius (Colles’ fracture) Universidade Federal de São Paulo — Escola Paulista de Medicina (Unifesp-EPM), São Paulo, Brazil CONTEXT AND OBJECTIVE: �������� �������� frac��r� i� a c�mm�n c�inica� �i��a�...

background: meict is the first chlorotoxin-like peptide isolated from the iranian scorpion mesobuthus eupeus. chlorotoxin (ctx) is a neurotoxin that specially binds to (mmp-2) on ma-lignant cells and now is used in treatment of glioma. in the present study, we have used homology modeling to propose the 3d structure of meictand analyze its interaction with mmp-2 and its snp types. methods:the st...

conclusions this meta-analysis indicated that the tnf-α-308 g/a polymorphism is significantly associated with increased susceptibility to hcc. however, to confirm this finding, more studies are needed on tnf-α-308 g/a polymorphisms associated with hcc. context hepatocellular carcinoma (hcc) is a common disorder throughout the world that can develop due to various factors, including genetics. tu...

conclusions the identified expression profiles of some examined mirnas might offer important points to consider for the treatment of naive patients and the management of chronically infected hcv patients in egypt and around the world. results our results revealed differential expression levels of the analyzed mirnas compared to the normal controls. twenty-seven mirnas (including mir-105, mir-14...

mercury is quantitatively retained with 1, 5-diphenylcarbazone (dpc) on microcrystallinenaphthalene in the ph range 6.5-8.5 from a large volume of aqueous solutions of various samples.after filtration, the solid mass consisting of the mercury complex and naphthalene was dissolvedin 5.0 ml of dimethylformamide (dmf) and mercury was determined by spectrophotometricmethod at 542 nm against the rea...

two common single nucleotide polymorphisms (snps) of the human tlr4 gene, namely asp299gly (d299g) and thr399ile (t399i), have been shown to impair the ability of certain individuals to respond properly to tlr4 ligands. 5-fluorouracil (5-fu) is widely used for the treatment of patients with advanced colon cancers. the present study examined the impact of two common polymorphisms of the tlr4 gen...

 The a im of th is paper was to study the effects w hey pro t e in c oat i ng on ch e m ic al a nd physic al properties of gut t ed K i l ka dur i ng f roz en stor a ge. Coating of Kilka has done by dipping in whey protein solution with different concentrations of 3, 7, 10 and 13%, for 1h. Then, after being packed in polyethylene dishes, they were covered in cellophane blanket and stored in -18...