In the preceding paper (1) a new method of preparing the normal pigment from urine has been described. It consisted essentially of extracting the pigment from acidified urine (pH about 4.0) with n-butyl alcohol, washing freely at different stages in the procedure with water, chloroform, benzol, amyl acetate, and amyl alcohol and finally obtaining the pigment product in a dry form by washing wit...

The drug itself is inexpensive, and goes a long way; it would require a large number of cases to get through an ounce during the year, and its price is only about one quarter that of quinine. I now use nitrite of amyl mixed with an equal part of oil of coriander, to render it less volatile, and at the same time to cover what is, to my sense of smell, a most disagreeable odour. I find it acts be...