Dementia is one of the age related mental problems and a characteristic symptom of various neurodegenerative disorders including Alzheimer’s disease. Desmodium gangeticum DC. (Leguminosae) is widely used in Ayurveda for treating various neurological disorders. In the present study, the effectiveness of aqueous extract of D. gangeticum in attenuating scopolamine-induced amnesia in mice was inves...

The experimental antiepileptic drug, levetiracetam (UCB L059), a piracetam analogue has been investigated in photosensitive patients in the "photosensitivity model", an early phase II study. A total of 12 patients (10 females, 2 males) with a mean age of 21.5 years (range 13-38) were investigated during a 3 day period in 3 centres (France, The Netherlands, Germany), using the same standardised ...

OBJECTIVE Most patients admitted to Intensive Care Units (ICU) have problems in using oral medication or ingesting solid forms of drugs. Selecting the most suitable dosage form in such patients is a challenge. The current study was conducted to assess the frequency and types of errors of oral medication administration in patients with enteral feeding tubes or suffering swallowing problems. ME...

AIMS The course of mild cognitive impairment (MCI) involves a slight loss of memory without any significant effects on other cognitive functions. Around 12% of these patients advance annually toward Alzheimer s disease, and for this reason it is important to search for medications that can prevent or slow down the evolution to dementia. Memory training programs, with relaxation techniques, the ...

dementia is one of the age related mental problems and a characteristic symptom of various neurodegenerative disorders including alzheimer’s disease. desmodium gangeticum dc. (leguminosae) is widely used in ayurveda for treating various neurological disorders. in the present study, the effectiveness of aqueous extract of d. gangeticum in attenuating scopolamine-induced amnesia in mice was inves...

In recent years, attempts have been made to develop drugs for treatment of dementia and attention deficit disorders to improve memory and learning. Some nootropic agents (eg: Piracetam) are widely used but the resulting chemo phobia associated with them and other similar agents has made their use limited. So it is worthwhile to explore medicines from the traditional system in the treatment of t...

Progressive myoclonic epilepsy (PME) is a group of disorders in which myoclonus is a major component. Patients with PME typically have generalized tonic–clonic or clonic seizures, mental retardation culminating in dementia, and a neurologic syndrome that almost always includes cerebellar dysfunction. It comprises a heterogeneous group of inherited disorders. Conditions inwhich PME is seen inclu...

Methomyl is a potent pesticide that is widely used in the field of agriculture. The systemic toxic effects of methomyl have been well described. However, the neurological effects of methomyl intoxication are not well understood. In this study, we report a 61-year-old Taiwanese man sent to our emergency department because of altered mental status. His family stated that he had consumed liquid me...