Bee venom (BV) from honey bee (Apis mellifera L.) has been used in oriental medicine and cosmetic ingredients because of its diverse pharmacological activities. In many studies, among BV components, phospholipase A2 (PLA2) is known as a major player in BV-induced allergic reaction. Therefore, we removed PLA2 from BV using ultrafiltration and then investigated in vitro phototoxicity and in vivo ...

Researchers equipped with these unique and ever improving tools can utilize optical microscopy and digital image analysis to study subcellular events within cells, cell-cell interactions and integrative organ physiology, biochemistry, molecular and cellular biology. This will greatly enhance the understanding of physiologic and disease processes, developmental biology, and will hasten and impro...

Imaging of living cells and tissue is now common in many fields of the life and physical sciences, and is instrumental in revealing a great deal about cellular dynamics and function. It is crucial when performing such experiments that cell viability is at the forefront of any measurement to ensure that the physiological and biological processes that are under investigation are not altered in an...

The uncontrolled exposure of Fischer's medium to cool white fluorescent (CWF) light or other sources emitting near-ultravi olet or visible light absorbable by riboflavin is a crucial random variable in experiments which utilize L5178Y cells and this medium. The radiation effects of CWF light result in the rapid development of toxic photoproducts in the medium which are cytostatic at lower doses...

The uncontrolled exposure of Fischer's medium to cool white fluorescent (CWF) light or other sources emitting near-ultraviolet or visible light absorbance by riboflavin is a crucial random variable in experiments which utilize L5178Y cells and this medium. The radiation effects of CWF light result in the rapid development of toxic photoproducts in the medium which are cytostatic at lower doses ...

She had been exposed to strong sunlight through a car windscreen for 2 h on the previous day and also on return to the hospital. The erythema was limited to areas of light exposure with a band of unaffected skin beneath her watch strap ( fig. 2 ). There was no phototoxicity at the covered injection sites. The patient was systemically well but did report passing red-coloured stools. A diagnosis ...