BACKGROUND The development of primary constipation in elderly adults usually has a multifactorial etiology. Slow transit constipation and pelvic floor dysfunction (PFD) are the two most commonly seen constipation subtypes in the elderly. PFD is usually a persistent condition that remains unresponsive to treatment in spite of various therapies currently available to relieve constipation. The aim...

The microalga Haematococcus pluvialis Flotow is one of the natural sources of astaxanthin, a pigment widely used in salmon feed. This study was made to discover optimal conditions for biomass and astaxanthin production in H. pluvialis from Steptoe, Nevada (USA), cultured in batch mode. Growth was carried out under autotrophic (with NaNO3, NH4Cl and urea) and mixotrophic conditions (with 4, 8, 1...

The [Het-s] prion of the fungus Podospora anserina represents a good model system for studying the structure-function relationship in amyloid proteins because a high resolution solid-state NMR structure of the amyloid prion form of the HET-s prion forming domain (PFD) is available. The HET-s PFD adopts a specific β-solenoid fold with two rungs of β-strands delimiting a triangular hydrophobic co...

Using thylakoid membranes, we previously demonstrated that accumulated electrons in the photosynthetic electron transport system induces the electron flow from the acceptor side of PSII to its donor side only in the presence of a pH gradient ((Delta)pH) across the thylakoid membranes. This electron flow has been referred to as cyclic electron flow within PSII (CEF-PSII) [Miyake and Yokota (2001...

Ventricular dilation affects 7% to 10% of patients with Chiari type I malformation (CIM), but the choice of surgical treatment is controversial. To study the surgical approaches for treating CIM with ventricular dilation and to evaluate the efficacy of posterior fossa decompression (PFD), clinical and imaging data of 38 adult patients who received surgical correction performed at the authors' d...

In R&D many disciplines focus on different aspects of managing the product life cycle. Generally, can be divided into technical and business aspects. Combining these two views, research areas beneficial in context productization. Productization links to concept structure relates modelling offering according a consistent structure, commercially technically. The goal this is identify how business...

The gasdermin family (GSDMs) contains a group of uncharacterized proteins that form membrane pores and serve as major substrate for inflammatory caspases the execution pyroptosis, which is recognized novel type programmed cell death [1]. Gasdermin (GSDM) consists A (GSDMA), B (GSDMB), C GSDMC), D (GSDMD), E(GSDME) Pejvakin (PJVK). With exception PJVK, all GSDMs consist two conserved domains: C-...

Objective: We examined associations between obesity, diabetes mellitus, and female pelvic floor disorders (PFD); stress urinary incontinence (SUI), overactive bladder (OAB), and anal incontinence (AI); in community dwelling women Research Design & Methods: Women were screened for PFD using a validated mailed survey. Diabetes status, glycemic control, and diabetes treatment were extracted from c...