objective(s): throughout evolution, mammalians have increasingly lost their ability to regenerate structures however rabbits are exceptional since they develop a blastema in their ear wound for regeneration purposes. blastema consists of a group of undifferentiated cells capable of dividing and differentiating into the ear tissue. the objective of the present study is to isolate, culture expand...

In order to establish and standardize the rabbit rib segmental bone defect model, it is of vital importance to determine rabbit rib critical size defect (CSD). According to the general time needed for spontaneous long-bone regeneration, three-month observation period was set to determine the CSD. The rabbit rib segmental bone defects with different sizes from 1 to 5 cm with or without periosteu...

Mrs MA, 70 years of age, has a history of scalp psoriasis dating over 10 years. She explained that the rash was slowly progressing and had failed to respond to an array of topical treatments offered. Within the right lateral aspect of the 12 x 14 cm lesion a thick nodule had recently developed. It looked like squamous cell carcinoma (SCC). Biopsy of the raised lesion confirmed SCC as did four o...

a mass in the anterior part of his right shoulder. Examination revealed a well-circumscribed lesion over the central one-third of the right clavicle, measuring approximately 8 × 7 cm. The mass was firm, nonpulsatile and immobile, appearing to be contiguous with, and fixed to, the clavicle. A plain radiograph of the clavicle is shown in Fig. 1 and a representative magnetic resonance image in Fig...

Cadaveric dissections and surgical observations have led to the description and clarification of the boundaries. blood supply, and nomenclature of the layers of the scalp. Special attention was directed to the layer of "loose connective tissue" that lies beneath the entire galea and above the cranial periosteum centrally, and the temporalis fascia laterally. It has been named the subgaleal fasc...

BACKGROUND The adaptive nature of bone formation under mechanical loading is well known; however, the molecular and cellular mechanisms in vivo of mechanical loading in bone formation are not fully understood. To investigate both mechanisms at the early response against mechanotransduction in vivo, we employed a noninvasive 3-point bone bending method for mouse tibiae. It is important to invest...