A study by Keam et al demonstrated that influenza vaccination, regardless of timing during 3-week cytotoxic chemotherapy cycles, may provide seroprotection. The majority of patients in this study were women with either breast or lung cancer. In an earlier study of patients with colorectal cancer, influenza vaccination was found to result in fewer cases of influenza, fewer cases of pneumonia, an...

The purpose of this study was to determine, for the first time, antioxidant activities of seven peptides (P1-P7) derived from hydrolysis of oat proteins in a cellular model. In the oxygen radical absorbance capacity (ORAC) assay, it was found that P2 had the highest radical scavenging activity (0.67 ± 0.02 µM Trolox equivalent (TE)/µM peptide) followed by P5, P3, P6, P4, P1, and P7 whose activi...

A person, who is talented, performs in a certain capacity above the norm. Talent is different from intelligence which is a response to a circumstance using knowledge and skill. The attributes of talent are exceptional memory, rapid processing speed, and high motivation, an affinity for learning, creativity and optimal cognition. There is some proof suggests that certain aspects of talent are re...

objective: many studies have focused on the epigenetic characteristics of donor cells to improve somatic cell nuclear transfer (scnt). we hypothesized that the epigenetic status and chromatin structure of undifferentiated bovine adipose tissue-derived stem cells (badscs) would not remain constant during different passages. the objective of this study was to determine the mrna expression pattern...

KIF20A (RAB6KIFL) belongs to the kinesin superfamily of motor proteins, which play critical roles in the trafficking of molecules and organelles during the growth of pancreatic cancer. Immunotherapy using a previously identified epitope peptide for KIF20A is expected to improve clinical outcomes. A phase I clinical trial combining KIF20A-derived peptide with gemcitabine (GEM) was therefore cond...

A positional scanning synthetic peptide combinatorial library containing approximately 52 million hexapeptides was used to identify potential inhibitory peptides for recombinant mouse prohormone convertase 1 (PC1) and PC2 and to provide information on the specificity of these enzymes. The library surveys revealed that a P6 Leu, a P4 Arg, a P2 Lys, and a P1 Arg were most inhibitory against PC1, ...