Background and Aim Acanthamoeba is one of free-living amoebas, which are very abundant in nature. As a amoeba, this parasite has high lethality, especially people with underlying diseases, so researchers always looking for way to combat it. Drug plants good fight species. In study, we aimed investigate the lethal effect extract Oliveria decumbens vent Peganum harmala alcoholic on Acanthamoeba. ...