Metadoxine (pyridoxol L-2-pyrrolidone-5-carboxylate) is an ion-pair salt of pyridoxine (vitamin B6) and 2-pyrrolidone-5-carboxylate (PCA, also known as L-PGA). Metadoxine modulates GABAergic activity, and does not increase levels of brain neurotransmitterssuch as dopamine, norepinephrine and serotonin. In animal studies, Metadoxine has shown no signs of abuse or addiction potential....