conclusions patients treated with ptu should be closely monitored and followed up, even if the drug has been used for several years. when patients develop progressive dyspnea with alveolar opacities on chest imaging that cannot be explained otherwise, alveolar hemorrhage should be an important differential diagnosis while investigating the case. early diagnosis and prompt discontinuation of the...

background: gastrointestinal and liver diseases (gild) constitute a noteworthy portion of causes of death and disability in iran. however, data on their prevalence and burden is sparse in iran. the global burden of disease (gbd) study in 2010 has provided invaluable comprehensive data on the burden of gild in iran methods: estimations of death, years of life lost due to premature death (yll), y...

ascites in the course of crohn's diseases is rare and is usually a sign of a concomitant malignancy, infection or thrombosis of portal or hepatic vein. herein, we reported on a 26-year-old man who was initially admitted with severe crohn's ileocolitis complicated by copious exudative ascites, abdominal pain and sever diarrhea. in our patient, we could not find any of the aforementioned conditio...

materials and methods in this case-control study, using the polymerase chain reaction (pcr), adrs266729 and rs2241766 gene polymorphisms were genotyped in b-type ultrasonography-proven nafld patients, with (n = 246) or without (n = 247) cad and in healthy controls (n = 304). serum lipid profiles were determined using biochemical methods. statistical analyses were performed using spss 17.0 stati...

background: infectious agents have been suspected as a triggering factor for development of autoimmune thyroid disease (atd). some reports from western countries have suggested association between helicobacter pylori (hp) infection and atd. objective: to investigate the association of atd with cag a seropositivity in a population with high rate and early age of onset of hp infection. methods: i...

Atherosclerosis is the most common cause of myocardial infarction and ischemic stroke. Various risk factors have been identified for atherosclerosis. Recently, bacterial and viral organisms, which are involved in chronic inflammatory processes, have been also implicated in atherosclerosis development. Individuals with a prior history of periodontal diseases and/or tooth loss are considered to be...

background only a few studies in western countrieshave investigated the association between gastroesophageal reflux disease(gerd) and mortality at the general population level and they have shown mixedresults. this study investigated the association between gerd symptoms andoverall and cause-specific mortality in a large prospective population-based studyin golestan province, iran. methods base...

introduction: today, air pollution is one of the critical problems in metropolitans and necessary preparations are needed for confronting with this crisis. the present study was based on the goal of determining the relation of air pollutant levels with the rate of emergency admission for respiratory and cardiovascular patients. methods: in the present retrospective cross- sectional study, all r...

purpose: risk factors of pelvic inflammatory disease can be different in different countries because of different sexual behaviors and religious restrictions. this study investigated the risk factors of this disease in iranian women in tehran. materials and methods: in this cross-sectional, descriptive study 1104 women with pelvic inflammatory disease were assessed from may 2010 to march 2011. ...

how to cite this article: ashrafi mr, tavasoli ar. infantile-onset pompe disease. iran j child neurol autumn 2012; 6:4(suppl. 1):7-9. pls see pdf.   refe r ences: 1. kishnani ps, steiner rd. pompe disease diagnosis and management guidelines. american j med genetic. 2006 .vol; 8; no5. 2. case se, beckemyer aa. infantile pompe disease on ert-updateonclinicalpresentation,musculoskeletal management...