This study investigated the possible antinociceptive effect of p-cymene in different tests of orofacial nociception. The animals (mice) were pretreated (i.p.) with p-cymene (25, 50, 100 mg/kg), morphine (5 mg/kg), or vehicle (0.2% Tween 80+saline), and were then subsequently administered, subcutaneously into their upper lip: formalin, capsaicin, and glutamate. The nociceptive behavior response ...

Key research findings relative to the question of whether maternal use of folic acid before and during pregnancy reduces the chance that offspring will be born with a congenital heart defect or an orofacial cleft are reviewed in this paper. Observational studies in general support an association between maternal use of multivitamins containing folic acid and a reduction in the occurrence of con...

BACKGROUND The combination of two analgesic agents offers advantages in pain treatment. Codeine and morphine analgesia is due to activation of opioid receptor subtypes. METHODS This study, performed in mice using isobolographic analysis, evaluated the type of interaction in intraperitoneal (ip) or intrathecal (it) coadministration of codeine and morphine, in three nociceptive behavioral model...

The aim of the present study was to evaluate effect of ellagic acid, a polyphenol bioactive compound, on reserpine-induced orofacial dyskinesia in Wistar male albino rats and to explore the possible underlying mechanisms for this effect. Reserpine (1 mg kgG1, i.p.) was administered on every alternate day for a period of 5 days (day 1, 3 and 5) to induce orofacial dyskinesia in rats. Ellagic aci...

BACKGROUND Infraorbital ethmoid cells, also known as Haller's cells can be seen on panoramic radiographs. These help in identification of various pathologies and patient symptoms. OBJECTIVE To determine the prevelance and characteristic of Haller's cells on panoramic radiographs. Infraorbital ethmoid cells are extensions of ethmoid air cells into areas of orbit and maxillary sinus. MATERIAL...

This report presents the results of treatment of two adults, at the Pain Center of Montreal General Hospital, Canada, with intravenous lidocaine for intractable orofacial pain. Repeated lidocaine infusions (1mg/kg in a bolus, followed by 4mg/kg infused over 1 hour) resulted in satisfactory pain relief in both patients, and the drug was well tolerated. Intravenous lidocaine therapy may be consid...

A syndrome is a set of signs and symptoms that tend to occur together and reflect the presence of a particular disease or an increased chance of developing to a particular disease. There are numerous orofacial syndromes and a thorough knowledge of their manifestations and implications is pertinent in good oral health care delivery. The aim of this review is to describe collective esoteric knowl...

Melkersson-Rosenthal syndrome (MRS) is a rare disease characterized by a triad of relapsing or persistent orofacial edema, recurrent lower motor neuron facial nerve palsy and fissured tongue. Acute, painless, non-erythematosus orofacial edema is observed in all patients. We report a case of a 13-year-old girl who presented with a 2-year history of swelling of the upper lip, facial paralysis, an...

Mariana Siviero, Manoel Jacobsen Teixeira, José Tadeu Tesseroli de Siqueira, Sı́lvia Regina Dowgan Tesseroli de Siqueira I Orofacial Pain Team, Faculdade de Medicina da Universidade de Sao Paulo, Brazil. II Neurology Department, Faculdade de Medicina da Universidade de Sao Paulo, Brazil. III Head of the Orofacial Pain Team, Dentistry Division, Faculdade de Medicina da Universidade de Sao Paulo, ...

Methods Twenty-eight consecutive patients (22 girls) who presented to our outpatient pediatric rheumatology clinic and fulfilled the ACR criteria of fibromyalgia were included in this study. All patients underwent a rheumatologic examination performed by a pediatric rheumatologist, and an orofacial examination performed by a single dentist at the same data. The patients were interviewed accordi...