The neglected tropical diseases (NTDs) are the most common infections of poor people in developing countries, where they cause a high disease burden that rivals HIV/AIDS, tuberculosis, or malaria [1]. The NTDs also exhibit important povertypromoting features, a consequence of their ability to adversely affect child development, pregnancy outcome, and worker productivity [1,2]. Over the last two...

A family is described with congenital hydrocephalus occurring in two pregnancies following the birth of a child with a neural tube defect (NTD). Prenatal diagnosis of hydrocephalus at mid-gestation was achieved by ultrasonography. The increased frequency of hydrocephalus among sibs of probands with a NTD and vice versa suggests that, following the birth of a child with either malformations, sub...

Abstract This paper presents an analytical model to quantify the measured noise in a cryogenic bolometer readout circuit. The includes contributions from bias resistors and sensor resistors, voltage current of amplifier, cable capacitance. parameters are empirically estimated using frequency domain analysis data indigenously developed Neutron Transmutation Doped (NTD) Ge sensors. is shown descr...

We introduce a scale-free method for testing the proportionality of branch lengths between two phylogenetic trees that have the same topology and contain the same set of taxa. This method scales both trees to a total length of 1 and sums up the differences for each branch. Compared to previous methods, ours yields a fully symmetrical score that measures proportionality without being affected by...

Steroid hormones are important endocrine signalling molecules controlling reproduction, development, metabolism, salt balance and specialized cellular responses, such as inflammation and immunity. They are lipophilic in character and act by binding to intracellular receptor proteins. These receptors function as ligand-activated transcription factors, switching on or off networks of genes in res...

Neural tube defects (NTD) are a heterogeneous group of malformations resulting from failure of normal neural tube closure before the fourth and fifth week of embryologic development. The three most common forms of NTD are: anencephaly, encephalocele and spinal dysraphism. Less common forms of neural tube defects include iniencephaly, amniotic bands and other types of spinal abnormalities inclu...

In this paper, we continue the study of neighborhood total domination in graphs first studied by Arumugam and Sivagnanam [S. Arumugam, C. Sivagnanam, Neighborhood total domination in graphs, Opuscula Math. 31 (2011) 519–531]. A neighborhood total dominating set, abbreviated NTD-set, in a graph G is a dominating set S in G with the property that the subgraph induced by the open neighborhood of t...

Androgen ablation therapy remains the gold standard for the treatment of advanced prostate cancer, but unfortunately, it is not curative, and eventually the disease will return as lethal castration-resistant prostate cancer (CRPC). Mounting evidence supports the concept that development of CRPC is causally related to continued transactivation of androgen receptor (AR). All current therapies tha...

Multi-way data arises inmany applications such as electroencephalography classification, face recognition, text mining and hyperspectral data analysis. Tensor decomposition has been commonly used to find the hidden factors and elicit the intrinsic structures of the multi-way data. This paper considers sparse nonnegative Tucker decomposition (NTD), which is to decompose a given tensor into the p...

Between days 24 and 28 post-conception the neural tube closes to form the spinal cord and the cranium. Incomplete closure of the former causes spina bifida and of the latter, anencephaly, the two conditions being collectively called neural-tube defects (NTD; O’Rahilly & Muller, 1994). While there is clearly a genetic component to the aetiology of NTD the prevalence within any stable genetic poo...