نتایج جستجو برای: neurobehavior

تعداد نتایج: 252  

2017
Hongyu Wang Chang Liu Xifan Mei Yang Cao Zhanpeng Guo Yajiang Yuan Ziming Zhao Changwei Song Yue Guo Zhaoliang Shen

Berberine exerts neuroprotective effect in neuroinflammation and neurodegeneration disease. However, berberine effect in acute spinal cord injury is yet to be elucidated. Herein, we investigated the neuroprotective effect of berberine in spinal cord injury (SCI). Sprague-Dawley rats were subjected to SCI by an intraperitoneal injection of berberine post-injury. The neurobehavioral recovery, cyt...

2005
Kim N. Dietrich Brenda Eskenazi Susan Schantz Kimberly Yolton Virginia A. Rauh Caroline B. Johnson Abbey Alkon Richard L. Canfield Isaac N. Pessah Robert F. Berman

Principles and practices of pediatric neurotoxicology are reviewed here with the purpose of guiding the design and execution of the planned National Children's Study. The developing human central nervous system is the target organ most vulnerable to environmental chemicals. An investigation of the effects of environmental exposures on child development is a complex endeavor that requires consid...

2013
Yuan-Xiao Yang Yi-Tao Chen Xiao-Jie Zhou Chun-Lan Hong Chang-Yu Li Jian-You Guo

BACKGROUND Ischemic hypoxic brain injury often causes irreversible brain damage. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients may explain a growing interest in traditional medicines. β-Asarone, which has significant pharmacological effects on the central nervous system (CNS), was used in the prevention of cerebral ischemia in this paper. ...

Journal: :The Journal of adolescent health : official publication of the Society for Adolescent Medicine 2012
Janet A Dipietro

There is significant current interest in the degree to which prenatal exposures, including maternal psychological factors, influence child outcomes. Studies that detect an association between prenatal maternal psychological distress and child developmental outcomes are subject to a number of interpretative challenges in the inference of causality. Some of these are common to many types of prena...

2013
Thanasekaran Jayakumar Wen-Hsien Hsu Ting-Lin Yen Jun-Yun Luo Yu-Cheng Kuo Tsorng-Harn Fong Joen-Rong Sheu

Hinokitiol ( β -thujaplicin), a tropolone-related compound found in the heartwood cupressaceous plants, is widely used in hair tonics, tooth pastes, cosmetics, and food as an antimicrobial agent. Increasing evidence has confirmed that hinokitiol exhibits anticancer activity in a variety of cancers through inhibition of cell proliferation. In the present study, we have investigated the neuroprot...

2009
Ananya Roy David Bellinger Howard Hu Joel Schwartz Adrienne S. Ettinger Robert O. Wright Maryse Bouchard Kavitha Palaniappan Kalpana Balakrishnan

BACKGROUND Lead exposure has long been associated with deficits in IQ among children. However, few studies have assessed the impact of lead on specific domains of behavior and cognition. OBJECTIVE We evaluated the associations between lead and different domains of neurobehavior and their relative sensitivity to lead. METHODS We determined blood lead levels using a LeadCare instrument in 756...

2016
Sander Ruiter Josefine Sippel Manon C. Bouwmeester Tobias Lommelaars Piet Beekhof Hennie M. Hodemaekers Frank Bakker Evert-Jan van den Brandhof Jeroen L. A. Pennings Leo T. M. van der Ven

Non-communicable diseases (NCDs) are a major cause of premature mortality. Recent studies show that predispositions for NCDs may arise from early-life exposure to low concentrations of environmental contaminants. This developmental origins of health and disease (DOHaD) paradigm suggests that programming of an embryo can be disrupted, changing the homeostatic set point of biological functions. E...

2012
Elisenda Eixarch Dafnis Batalle Miriam Illa Emma Muñoz-Moreno Ariadna Arbat-Plana Ivan Amat-Roldan Francesc Figueras Eduard Gratacos

BACKGROUND Intrauterine growth restriction (IUGR) affects 5-10% of all newborns and is associated with a high risk of abnormal neurodevelopment. The timing and patterns of brain reorganization underlying IUGR are poorly documented. We developed a rabbit model of IUGR allowing neonatal neurobehavioral assessment and high resolution brain diffusion magnetic resonance imaging (MRI). The aim of the...

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