PURPOSE Artificial grafts have been investigated for use in the repair of oral mucosal defects. The aim of this retrospective study was to present the outcomes of the use of acellular dermal matrix (ADM) grafts to repair oral mucosal defects. MATERIALS AND METHODS Data from 36 patients with oral mucosal defects reconstructed with ADM grafts from 2003 through 2009 were reviewed. All patients w...

BACKGROUND Although mucosal thickening is the most common radiographic finding observed regarding sinus pathology, the knowledge regarding its clinical significance on the outcomes of dental implants and grafting in the maxillary sinuses is still limited. We hypothesized that mucosal thickening would not alter the predictability for sinus floor augmentation and dental implant placement. The pur...

Oral lichen planus (OLP) is an immune-mediated disease of the oral mucosa with idiopathic aetiology. It frequently treated topical corticosteroids (applied as gels, mouthwashes, or sprays); however, mucosal exposure times are short because removal by constant flow saliva and mechanical forces. In this study we used cell monolayers, well equivalents (OMEs) containing activated T-cells, to examin...

Edible vaccines are sub-unit vaccines where the selected genes are introduced into the plants and the transgenic plant is then induced to manufacture the encoded protein. Edible vaccines are mucosal targeted vaccines where stimulation of both systematic and mucosal immune network takes place. Foods under study include potatoes, bananas, lettuce, rice, wheat, soybean, corn and legumes. Edible va...

Crohn disease and ulcerative colitis are chronic inflammatory bowel diseases (IBD) characterized by recurrent episodes of mucosal inflammation. This chronic mucosal inflammation has several potential consequences, one of which is the occurrence of colitis-associated colorectal cancer. Over the past decade, our understanding of the epidemiology, pathophysiology, and overall approach to diagnosin...