Polyether ionophores, monensin, and salinomycin are commonly used as antiparasitic drugs in broiler production and may be present in broiler litter (bird excreta plus bedding material). Long-term application of broiler litter to pastures may lead to ionophore contamination of surface waters. Because polyether ionophores break down at low pH, we hypothesized that decreasing litter pH with an aci...

Processing of the measles virus haemagglutinin (H) protein was analysed by the pulse-chase method, immunoprecipitation with an anti-H monoclonal antibody and SDS-polyacrylamide gel electrophoresis, combined with the addition of carbonyl cyanide m-chlorophenylhydrazone (CCCP) or monensin (inhibitors of intracellular processing of secretory proteins) to cultures and digestion of the protein with ...

Monensin 3 , a polyether antibiotic, was blended with a forage diet at levels of 0, 11, 22 and 33 ppm and fed to steers to determine its effect on cot ton fiber, dietary carbohydrate and nitrogen digestibility, on numbers of rumihal microbes, and on concentration of ruminal volatile fa t ty acids. No differences (P>.10) in cellulose digestibility from cot ton were observed in response to monens...

A liquid chromatography-mass spectrometric method was developed and validated to determine six polyether ionophores (lasalocid sodium, monensin sodium, salinomycin sodium, narasin, maduramicin ammonium alpha, and semduramicin sodium) in feed samples. The method developed was very straightforward, involving extraction with 84% acetonitrile of the coccidiostats from the feed samples and filtratio...

background: high grain diets in ruminants increases the risk of digestives disorders such as acidosis which may lead to high economic loss. objectives: this experiment was conducted to determine the effects of an unsaturated and polyunsaturated fatty acid and monensin on gene expression of enzymes involved metabolic pathway of cell proliferation and rumen epithelial intracellular ph regulation....

the effect of inclusion of garlic essential oil (eo) at 33, 66 and 100 μg ml-1, raw garlic (gar) at 5, 10 and 15 mg ml-1 and monensin (mon) at 7.5 μg ml-1 of incubation medium on organic matter digestibility (omd) was studied with in vitro gas production, ankom daisyii and conventional in vitro (ivomd) methods. the material was incubated with sheep ruminal fluid and the experimental design was ...

The prevention of subclinical ketosis (SCK) is based on maintaining adequate nutrition in dairy cows during the dry period and close to calving. Recently, an oral-route monensin bolus to prevent SCK was approved in Europe. The present study aims to define the allocation of resources for SCK management at the herd level and evaluate the profitability of administering monensin boluses in cows at ...

Monensin, a specific sodium ionophore~ has been shown to reduce glucose-induced proinsulin biosynthesis by 30% and to completely inhibit ~he intracellular conversion of proinsul in to insulin. Autoradiography of monensint r e a t e d cells d e m o n s t r a t e d the p resence of large quantities of newly synthesized proteins in amorphous vesicles close to the Golgi complex of B ceils. The r e ...

Effects of a blend live yeast and organic minerals as an alternative to monensin inorganic trace for beef cattle finished on pasture with high concentrate supplementation, growth performance, intake, digestibility, liver mineral carcass characteristics were evaluated. Forty-eight Nellore bulls blocked by initial body weight randomly assigned one the two experimental diets. The animals raised in...

Ahuja A. K., S. S. Randhawa, S. S. Rathor: Effect of Monensin in Ameliorating Subacute Lactic Acidosis in Buffalo Calves. Acta vet. Bmo, 59, 1990: 171-178. The efficacy of monensin feeding on rumen metabolism, acid base status and gas tension of blood in molasses induced subacute lactic acidosis in buffalo-calves was evaluated. Subacute lactic acidosis was induced by oral administration of mola...