BACKGROUND The present study sought to investigate erythrocyte glutathione S-transferases (GST), NADH-Methaemoglobin reductase (NADH-MR) and Na(+)/K(+)-ATPase activities of hypoglycemic rats treated with ethanol/water (1:2 v/v) extract of A. sativa as agent of glycemic control. METHODS Hyperglycemia was induced by a single intra-peritoneal injection of 0.1 mol/L alloxan monohydrate in phospha...

Nitric oxide (NO) has been identified as a neurotransmitter of nonadrenergic noncholinergic bronchodilator nerves. To investigate whether inhaled NO exerts a bronchodilator effect in patients with chronic obstructive pulmonary disease (COPD), we measured the resistance of the respiratory system, using the forced oscillation technique, while breathing NO. Eight patients with COPD (7 men and 1 wo...

Haemoglobin has been the subject of intensive research for many years and is one of the most thoroughly understood of all protein molecules. The amino-acid sequences of haemoglobins from many species of animals have been determined (tabulated by Dayhoff, 1969) and the molecular structures of horse and human haemoglobins have been determined in great detail by x-ray crystallography (Perutz et al...

Original Article AIMS AND OBJECTIVES:1. To screen blood donors [n=100] for G6PD deficiency, particularly in males. 2. To determine the frequency of G6PD deficiency in the population tested. MATERIALS AND METHODS: 50 samples of donors' blood from at KIMS Blood Bank. Method of collection of data: The Methaemoglobin reduction test: Principle: Sodium Nitrate oxidises MethHb to Hb and the subsequent...

BACKGROUND Diabetes is associated with an increased generation of reactive oxygen species (ROS), which plays an important role in the development of oxidative stress and anemia. OBJECTIVES The main purpose of this study was to investigate whether patients with diabetes undergoing hemodialysis (HD) were susceptible to oxidative stress and whether resulting damages affect the structure of hemog...

eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication. Acta Anaesthesiol Scand 1987;31: 735-9. 8 Hallen B, Olsson GL, Uppfeldt A. Pain-free venepuncture. Effect of timing of application of local anaesthetic cream. Anaesthesia 1984;39:%9-72. 9 Hopkins CS, Buckley CJ, Bush GH. Pain-free injection in infants. Use of a lignocaine-priloca...

Autoxidation of oxyhaemoglobin (oxyHb) to methaemoglobin was measured at different temperatures in haemoglobin solutions from Atlantic hagfish, river lamprey, common carp, yellowfin tuna and pig. The aims were to evaluate the impact of the absent distal histidine in hagfish haemoglobin, the importance of oxyHb being either monomeric (hagfish and lamprey) or tetrameric (carp, tuna and pig) and t...

Adding nitrate to the diet or increasing the concentration of dietary lipid are effective strategies for reducing enteric methane emissions. This study investigated their effect on health and performance of finishing beef cattle. The experiment was a two×two×three factorial design comprising two breeds (CHX, crossbred Charolais; LU, Luing); two basal diets consisting of (g/kg dry matter (DM), f...

Others have shown that inhaled nitric oxide causes reversal of pulmonary hypertension in anaesthetized perinatal sheep. The present study examined haemodynamic responses to inhaled NO in the normal and constricted pulmonary circulation of unanaesthetized newborn lambs. Three experiments were conducted on each of 7 lambs. First, to determine a minimum concentration of NO which could reverse acut...

An investigation was carried out in an aluminium recovery works after the simultaneous occurrence of haemolytic anaemia in two workers in the slag disposal plant. The first worker was admitted to hospital suffering from nausea, backache, and haematuria. Jaundice developed on the next day. His urine contained protein, urobilin, haemoglobin, and methaemoglobin but no red cells. During the course ...