Ascorbate is a crucial antioxidant for scavenging hydrogen peroxide generated from the physiological processes and environmental stresses. Besides, the endo/exogenous factors that influence ascorbate level, our knowledge of the methanol stimulation is relatively less. Methanol, a byproduct from the demethylation of pectin during the enlargement of plant cell, is effective in enhancing the expre...

A diminished chemotactic response was observed with the neutrophils of a patient with the Chediak-Higashi syndrome, who was not in the accelerated phase of the disease. An abnormally low release of myeloperoxidase from these cells during phagocytosis was also noted; this resulted in a decreased iodination capacity and probably also caused the defect in the intracellular killing of bacteria by t...

BACKGROUND The IL-15/NF-κB axis has an important role in coeliac disease (CD) and may represent a molecular target for immunomodulation. Ascorbate (vitamin C) is known to show inhibitory effects on NF-κB. Therefore, we studied if ascorbate supplementation to gliadin gliadin-stimulated biopsy culture could down-regulate the mucosal immune response to gliadin in CD. METHODS Duodenal biopsy expl...

This paper investigates the possibility for iron fortification of food using a new preparation method for protein gel particles in which iron is entrapped in the presence of ascorbate using cold-set gelation. The effect of ascorbate on the iron-induced cold-set gelation process of whey protein was studied in order to optimize the ratio of iron/ascorbate. Subsequently, the effect of ascorbate on...

Objective(s) It is believed that the mesenchymal stem cell (MSC) differentiation and proliferation are the results of activation of wnt signaling pathway. On the other hand, lithium chloride is reported to be able to activate this pathway. The objective of this study was to investigate the effect of lithium on in vitro proliferation and bone differentiation of marrow-derived MSC. Materials and ...

Electrochemical energy storage systems are categorized into different types, according to their mechanisms, including capacitors, supercapacitors, batteries and fuel cells. All battery systems include some main components: anode, cathode, an aqueous/non-aqueous electrolyte and a membrane that separates anode and cathode while being permeable to ions. Being one of the key parts of any new electr...

Numerous studies have been done on using low serum lithium levels for maintenance therapy of bipolar mood disorder over the past 30-40 years. In this study we sought for the most suitable serum lithium level that having longer relapse's interval periods and less side effects as to recommended it as a maintenance serum lithium level. Thus, we studied 90 patients with bipolar mood disorder (accor...

During development and fracture repair, endochondral bone formation is preceded by an orderly process of chondrocyte hypertrophy and cartilage matrix calcification. Analysis of calcifying versus noncalcifying cartilage has identified several differences in matrix proteins; among these are appearance of a novel collagen, type X, and decreased synthesis of type II collagen, the major component of...