Objective: To explore whether individual choice treatment is a feasible choice in the treatment of different types of chronic osteomyelitis with different causes and history as well as the differences in local soft tissue conditions. Methods: Seventy-three cases of different types of chronic osteomyelitis were included in the study. According to the classification of causes: 21 cases were blood...

In this paper, we argue that causal effect models for realistic individualized treatment rules represent an attractive tool for analyzing sequentially randomized trials. Unlike a number of methods proposed previously, this approach does not rely on the assumption that intermediate outcomes are discrete or that models for the distributions of these intermediate outcomes given the observed past a...

abstract background: hypertension is very common in patients with end-stage renal disease and accelerates cardiovascular morbidity and mortality. the most important factor in achieving normal blood pressure in these patients is reaching dry weight. sodium and extracellular fl uid balance play a vital role in this regard. considering the lack of consensus about the effi cacy of stepwise sodium p...

Approximately 75% of adults over the age of 65 years are affected by two or more chronic medical conditions. We provide a conceptual justification for individualized absolute risk calculators for competing patient-centered outcomes (PCO) (i.e. outcomes deemed important by patients) and patient reported outcomes (PRO) (i.e. outcomes patients report instead of physiologic test results). The absol...

OBJECTIVE Observation of weight loss and the maximum time that individualized dietary treatment qualitative and quantitative is shown to be effective. METHOD 4625 consultations were conducted with 616 patients over 25 years old, in the nutrition consultation, using the qualitative and quantitative individualized dietary treatment. As a result we controlled the weight loss, the fat and the qua...

PURPOSE To demonstrate a method of generating patient-specific, biologically-guided radiotherapy dose plans and compare them to the standard-of-care protocol. METHODS AND MATERIALS We integrated a patient-specific biomathematical model of glioma proliferation, invasion and radiotherapy with a multiobjective evolutionary algorithm for intensity-modulated radiation therapy optimization to const...

OBJECTIVE To develop and evaluate the Diabetes Social Support Questionnaire-Family Version (DSSQ-Family) for adolescents with type 1 diabetes. METHODS Normative and individualized approaches to scoring were examined. Also examined were associations between diabetes-specific family support and adolescents' age, disease duration, gender, emotional support from family and friends, and treatment ...