Specific monoclonal antibodies (MAbs) to mefloquine conjugated to bovine serum albumin (mefloquine-BSA) were produced by hybridoma technology. The mefloquine-BSA was synthesized by converting mefloquine into hemisuccinate followed by convalently linked to bovine serum albumin (BSA) and coupling with N,N' disuccinimidyl carbonate (DSC). The conjugate was purified by Sephadex G-75 gel filtration ...

CYTOP fiber, used mainly in strain detection and refractive index characterization of liquids, can be polished for the UV light radiation. The study investigates transmission spectra fiber exposed to different intensities light, demonstrating a linear relationship. A simplified system using single wavelength, 395 nm, shows real-time performance sensor range from 1 15 mW. results reveal potentia...

Because we found UV-exposed oral tissue cells have reduced DNA repair and apoptotic cell death compared with skin tissue cells, we asked if a correlation existed between personal UV dose and the incidences of oral and pharyngeal cancer in the United States. We analyzed the International Agency for Research on Cancer's incidence data for oral and pharyngeal cancers by race (white and black) and ...

Solar radiation induces acute and chronic reactions in human and animal skin. Chronic repeated exposures are the primary cause of benign and malignant skin tumors, including malignant melanoma. Among types of solar radiation, ultraviolet B (290-320 nm) radiation is highly mutagenic and carcinogenic in animal experiments compared to ultraviolet A (320-400 nm) radiation. Epidemiological studies s...

Indirect observation: Combination of indirect DNP, detection through 29Si, and 29Si-CPMG acquisition enabled measurements non-protonated oxygen at natural abundance.

Quantification of substances such as drug impurities or library compounds when pure standards are unavailable is difficult yet often necessary. This is often accomplished by HPLC based on relative response using low wavelength UV detection. The dependence of response on the optical properties of each component can lead to large errors in estimated quantity. Charged aerosol detection is a mass s...

Numerous applications in scientific, medical, and military areas demand robust, compact, sensitive, and fast ultraviolet (UV) detection. Our (Al)GaN photodiodes pose high avalanche gain and single-photon detection efficiency that can measure up to these requirements. Inherit advantage of back-illumination in our devices offers an easier integration and layout packaging via flip-chip hybridizati...

The Pennsylvania Game Commission contacted Millersville University to perform tests to help combat the transmission and spread of Chronic Wasting Disease (CWD) via better detection of urine-based deer lures. The objective of this study was to use multiple methods and kits designed for detection of urine and blood to determine the best method of detection for urine-based deer lures. Methods incl...