نتایج جستجو برای: hypertrophy of hyponychium
تعداد نتایج: 21168072 فیلتر نتایج به سال:
Background: Protein synthesis and degradation are dynamically regulated processes that to control the accretion or loss of muscle mass. However, the mechanisms responsible exercise-induced heart hypertrophy remains elusive. The aim of this study was to investigate the effect of aerobic training on expression of some indices of myocardial hypertrophy and atrophy in male rats. Materials and Meth...
Background: Clinical evidence points to the effective role of genetic factors and intracellular signaling pathways in physiological cardiac hypertrophy. This study aimed to assess the response of PI3K/mTORc1 signaling pathway in cardiac tissue to resistance training in obese diabetic rats. Materials and Methods: For this purpose, 21 male wistar rats (220±20 g) were obese by 6 weeks high fat di...
Cardiac hypertrophy accompanied by maladaptive cardiac remodeling is the uppermost risk factor for the development of heart failure. Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) have various biological functions, and their vital role in the regulation of cardiac hypertrophy still needs to be explored. In this study, we demonstrated that lncRNA Plscr4 was upregulated in hypertrophic mic...
Chondrocyte hypertrophy is an essential process required for endochondral bone formation. Proper regulation of chondrocyte hypertrophy is also required in postnatal cartilage homeostasis. Indian hedgehog (Ihh) and PTHrP signaling play crucial roles in regulating the onset of chondrocyte hypertrophy by forming a negative feedback loop, in which Ihh signaling regulates chondrocyte hypertrophy by ...
BACKGROUND Several reports have suggested that plasma B-type natriuretic peptide (BNP) levels are elevated in hypertensive patients especially with left ventricular (LV) hypertrophy. However, few data have been available concerning the utility of plasma BNP measurement to identify LV hypertrophy in hypertensive patients in a general population screening context. METHODS We measured plasma BNP...
The heart has two major modalities of hypertrophy in response to hemodynamic loads: concentric and eccentric hypertrophy caused by pressure and volume overload (VO), respectively. However, the molecular mechanism of eccentric hypertrophy remains poorly understood. Here we demonstrate that the Akt-mammalian target of rapamycin (mTOR) axis is a pivotal regulator of eccentric hypertrophy during VO...
BACKGROUND Electrocardiogram is the initial test in the investigation of heart disease. Electrocardiographic changes in hypertrophic cardiomyopathy have no set pattern, and correlates poorly with echocardiographic findings. Cardiac magnetic resonance imaging has been gaining momentum for better assessment of hypertrophy, as well as the detection of myocardial fibrosis. OBJECTIVES To correlate...
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