Porous polymer coatings are used to control drug release from pharmaceutical products. The coating covers a core and depending on the porous structure, different rates obtained. This work presents mass transport simulations performed ethyl cellulose films with porosities. were high spatial resolution 3D data obtained using focused ion beam scanning electron microscope. effective diffusion coeff...

The aim of the study was to prepare indomethacin nanocrystal-loaded, 3D-printed, fast-dissolving oral polymeric film formulations. Nanocrystals were produced by wet pearl milling technique, and 3D printing performed semi-solid extrusion method. Hydroxypropyl methyl cellulose (HPMC) film-forming polymer, glycerol plasticizer. In-depth physicochemical characterization made, including solid-state ...

We report an unusual case of granulomatous inflammation that presented adjacent to bleb 3 weeks postoperatively after combined phacoemulsification and trabeculectomy surgery with mitomycin-C due to retained microfragments of methyl cellulose sponge. The commonly used antimetabolite delivery devices are made of cellulose. Methyl cellulose sponges are friable, and they are likely to leave behind ...

BACKGROUND Derivatized celluloses, such as methylcellulose (MC) and hydroxypropyl methylcellulose (HPMC), are of pharmaceutical importance and extensively employed in tablet matrices. Each batch of derivatized cellulose is thoroughly characterized before utilized in tablet formulations as batch-to-batch differences can affect drug release. The substitution pattern of the derivatized cellulose p...

In recent years, great progress has been made in the dissolution of cellulose with ionic liquids (ILs). However, the mechanism of cellulose dissolution, especially the role the IL cation played in the dissolution process, has not been clearly understood. Herein, the mixtures of cellulose with a series of imidazolium-based chloride ionic liquids and 1-butyl-3-methyl pyridinium chloride ([C(4)mpy...