The ability of the easily reducible tetracyanoethylene (TCNE) ligand to bridge up to four metal centers and to adopt any oxidation state between 0 and -2 has generated a unique coordination chemistry with potential applications in molecular magnetism, electrochromism, and molecular computing. The coordination chemistry of electroactive, tetradonorsubstituted olefins is much less explored but ma...

Background Despite increasing treatment options for RA, many patients still do not appear to achieve remission, especially in more established disease. [1] Objectives To evaluate disease outcomes and quality of life (QoL) DMARD treated with RA clinical remission (CR) routine Irish rheumatology clinics vs those residual activity. Methods A multicentre, cross-sectional study a 9-month recruitment...

The polypeptide patterns of MCF-7 human breast cancer cells (MCF7gpt) and a stably v-H-roi-transfected subclone (MCF-7ras) have been analyzed following estradili! treatment. Since both estradili! and \-H-ras transfection increase tumorigenicity of MCF-7 cells, this study was designed to ascertain if specific changes in polypeptides were common in both treatments. Separation of cellular and secr...

Mountains provide as much as 90-100% of the freshwater to surrounding basins in arid and semiarid regions because of their distinctive and complex topography, and the consequent effects on precipitation (P) and evapotranspiration (ET). One of the primary objectives of this dissertation is to estimate mountain-block recharge (MBR), an important component of the mountain contribution to groundwat...

A series of octahedral ruthenium silyl hydride complexes, cis-(PMe(3))(4)Ru(SiR(3))H (SiR(3) = SiMe(3), 1a; SiMe(2)CH(2)SiMe(3), 1b; SiEt(3), 1c; SiMe(2)H, 1d), has been synthesized by the reaction of hydrosilanes with (PMe(3))(3)Ru(eta(2)-CH(2)PMe(2))H (5), cis-(PMe(3))(4)RuMe(2) (6), or (PMe(3))(4)RuH(2) (9). Reaction with 6 proceeds via an intermediate product, cis-(PMe(3))(4)Ru(SiR(3))Me (S...

Models are commonplace in hydrological and environmental sciences. In scientific contexts, models used to encapsulate our current understanding of processes test new propositions. applied predict future conditions hence a cornerstone the decision-making chain civil protection (e.g., real-time flood forecasting) management planning seasonal streamflow forecasts inform water allocation, ecologica...

Background: Osteoarthritis (OA) is a common disease that varies in severity among patients. A standardized definition to classify patients into different levels lacking, however, due the disease’s complex pathogenesis and presentation. Prior studies have shown associations between pain higher healthcare resource utilization (HRU) costs. We investigated an association by examining use of specifi...