To understand the biokinetics and potential risks of p,p'-dichlorodiphenyltrichloroethane (DDT) and its metabolites, p,p'-dichlorodiphenyldichloroethylene (DDE) and p,p'-dichlorodiphenyldichloroethane (DDD), in fish, we exposed the black sea breams (Acanthopagrus schlegeli) to aqueous and dietary DDTs and then evaluated the bioaccumulation, distribution, biotransformation, and elimination of DD...

Pharmaceutically active compounds (PhACs) have been shown to accumulate in aquatic and riparian food-webs. Yet, our understanding of how temperature, a key environmental factor nature, affects uptake, biotransformation, the subsequent accumulation PhACs organisms is limited. In this study, we tested what extent bioconcentration an anxiolytic drugs (temazepam oxazepam) affected by two temperatur...

primary hepatic lymphoma (phl) was a rare malignancy usually presenting with abdominal pain, malaise, hepatomegaly, b-symptoms, fatigue, nausea, vomiting and jaundice. it mostly involves liver without any palpable lymphadenopathy and leukemia in peripheral blood smear. on july 22, 2014, a 64 year old man presented with abdominal pain localizing in right upper quadrant and fullness from 2 years ...

a 34-year-old hiv positive-man was admitted to the hospital due to fever and abdominal pain. constant and generalized abdominal pain started 3 months prior to admission (pta) in upper quadrants of abdomen followed by mild odynophagia, early satiety and more than 20 kg weight loss since then. intermittent fever begun 7 days pta and cough, sputum and dyspnea started since 5 days pta. his general ...

Little is known of the normal seasonal variation in redox state and biotransformation activities in birds. In long-distance migratory birds, in particular, seasonal changes could be expected to occur because of the demands of migration and reproduction. In this study, we measured several redox parameters in the barn swallow (Hirundo rustica L.) during the annual cycle. We captured the wintering...

Many metals and metalloids undergo complex biotransformation processes by micro organisms in the environment, namely, Ge, As, Se, Cd, In, Sn, Sb, Te, Hg, Tl, Pb, Bi, and Po. Though the human intestine harbors a highly diverse and metabolically active micro bial community, the knowledge on metal(loid) biotransformation by gut microbiota is limited. Microbial metal(loid) metabolism in the gut is ...

A new potent Pseudomonas aeruginosa isolate capable for biotransformation of corn oil phytosterol (PS) to 4-androstene-3, 17-dione (AD), testosterone (T) and boldenone (BOL) was identified by phenotypic analysis and 16S rRNA gene sequencing. Sequential statistical strategy was used to optimize the biotransformation process mainly concerning BOL using Factorial design and response surface method...

Fourier transform-infrared (FT-IR) spectroscopy has become an important tool for rapid analysis of complex biological samples. The infrared absorbance spectrum could be regarded as a "fingerprint" which is characteristic of biochemical substances. In this study, Pseudomonas putida NCIMB 9869 was grown with either 3,5-xylenol or m-cresol as the sole carbon source, each inducing different metabol...

cell cultures of varthemia persica, peganum harmala and pycnocycla spinosa have been studied to evaluate their abilities to bioconvert exogenous hydroquinone. arbutin is an important substance that has several pharmaceutical applications; therefore, we have established v. persica and p. spinosa cultures which seem to be able to metabolize hydroquinone. callus cultures of v. persica were establi...

A fugacity model reported in the literature was applied to a high-altitude pasture in the Italian Alps. The model takes into account three compartments (digestive tract, blood and fat tissues) in unsteady-state conditions using food as the contamination source. Disregarding biotransformation inside cow tissues, the predicted concentrations of 14 polychlorinated biphenyls (PCBs) in milk were in ...