the results of many studies suggested possible relationship between polymorphism at codons 16 and 27 and development of tolerance to beta-2 adrenoceptor agonist responses as well as disease severity in asthmatic patients. this study was designed to evaluate the effect of polymorphism of beta2 adrenoceptors on response to salmeterol and fluticasone (as inhaled seretide). sixty-four patients with...

c3 typing was performed, by agarose gel electrophorisis, in 147 german patients suffering from hyperlipoproteinemia. the control group consisted of 322 healthy germans. high frequencies of non-typeable sera, varying between 16.66 and 35.71% in different hlp types, found in the present investigation are notable and are a clue for chemical denaturation of c3 protein in hlp patients. statistical a...

introduction: association between single-nucleotide polymorphisms (snps) in mu opioid receptor gene and drug addiction has been shown in various studies. here, we have evaluated the existence of polymorphisms in exon 3 of this gene in iranian population and investigated the possible association between these mutations and opioid addiction.  methods: 79 opioid-dependent subjects (55 males, 24 fe...

There are about 484 species of Hypericum in the Guttiferae family, which includes Hypericoideae. In Iran, this genus mainly found north, northwest, and center country, they key contributors to floral elements Hyrcanian mountains, Irano-Turanian, Mediterranean regions (such as Zagros). Medicinal, commercial, horticultural values associated with these plants.The genetic diversity was assessed thr...

Objective
 Type 2 diabetes mellitus (T2DM) and diabetic
 retinopathy (DR) development is affected by genetic
 factors. Matrix metalloproteinases (MMPs) are involved
 in many cellular processes, such as remodeling of
 extracellular matrix proteins angiogenesis. In
 this study, we investigated the relationship between
 MMP9 −1562 C/T (rs3918242) polymorphism the...

Relevance and methods . For molecular genetic analysis, samples taken from Romanov sheep in micro-populations of the Yaroslavl region ear by pluck were isolated. Polymorphism genes type 3 protein that inhibits insulin-like growth factor (IGFBP-3), hormone (Gh), calpastatin (CAST) was studied. A selection assessment live weight indicators age periods, depending on genotype, carried out. Results ...

Donor–acceptor–donor molecules containing heavy chalcogen atoms, which feature multi-color polymorphism, external-stimuli responsive luminochromism, thermally-activated delayed fluorescence, and room-temperature phosphorescence, have been developed.

  Abstract   Background: The disrupted-in-schizophrenia 1 (DISC1) gene, on the chromosome   position 1q42, was initially identified at the breakpoint of a balanced translocation,   t(1,11)(q42.1q14.3), which segregated with major mental disorders in a large   Scottish family.   Methods: Our samples included 200 unrelated patients diagnosed with Schizophrenia   on the basis of DSM-IV criteria an...