There are two competing hypotheses for the origin of the Indo-European language family. The conventional view places the homeland in the Pontic steppes about 6000 years ago. An alternative hypothesis claims that the languages spread from Anatolia with the expansion of farming 8000 to 9500 years ago. We used Bayesian phylogeographic approaches, together with basic vocabulary data from 103 ancien...

The defective acute leukemia viruses avian myeloblastosis virus (AMV) and E26 virus each contain an inserted cellular sequence related to the same highly conserved cellular gene, proto-amv. The oncogenes of these two retroviruses differ from this cellular proto-oncogene in gene structure, transcript structure, and gene product. The product of the AMV oncogene (myb) is a 48,000 Mr protein, p48my...

BACKGROUND Focusing on novel drug combinations that target different pathways especially apoptosis and MAPK could be a rationale for combination therapy in successful treatment of lung cancer. Concurrent use of cyclooxygenase (COX) inhibitors with arsenic trioxide (ATO) might be a possible treatment option. METHODS Cytotoxicity of ATO, dexamethasone (Dex), celecoxib (Cel), and Indomethacin (I...

Abstract From a linguistic standpoint, Proto-Japonic and Proto-Koreanic are assumed to have split off the Transeurasian languages in southern Manchuria. The idea that came earlier than chronological scheme means language first entered Korean Peninsula, from there spread Japanese archipelago at beginning of Yayoi period, around ninth century BC, while arrival Korea is associated with rolled rim ...

While Greek is rich in compounds, one familiar type from Indo-European, namely dvandva compounds meaning 'X and Y', is essentially nonexistent in Ancient Greek. However, such compounds start occurring in post-Classical Greek and are fairly productive by early Modern Greek. The innovative dvandvas involve nouns, a type well attested elsewhere in Indo-European, but also verbs, such as aniγo-klino...