نتایج جستجو برای: formylation

تعداد نتایج: 299  

2016
Lindsey Van Haute Sabine Dietmann Laura Kremer Shobbir Hussain Sarah F Pearce Christopher A Powell Joanna Rorbach Rebecca Lantaff Sandra Blanco Sascha Sauer Urania Kotzaeridou Georg F Hoffmann Yasin Memari Anja Kolb-Kokocinski Richard Durbin Johannes A Mayr Michaela Frye Holger Prokisch Michal Minczuk

Epitranscriptome modifications are required for structure and function of RNA and defects in these pathways have been associated with human disease. Here we identify the RNA target for the previously uncharacterized 5-methylcytosine (m(5)C) methyltransferase NSun3 and link m(5)C RNA modifications with energy metabolism. Using whole-exome sequencing, we identified loss-of-function mutations in N...

Journal: :The Journal of biological chemistry 1975
M Sono T Asakura

Three kinds of green synthetic myoglobin were prepared by recombination of horse heart apomyoglobin with spirographis (2-formyl-4-vinyl-), isospirographis (2-vinyl-4-formyl-), and 2,4-diformyldeuterohemins. The optical and oxygen binding properties of the reconstituted myoglobins containing two isomeric monoformyl-monovinylhemins were found to be different. The oxygen affinities (P50) of spirog...

Journal: :The Journal of biological chemistry 1977
R Bianchetti G Lucchini P Crosti P Tortora

The effect of N10-formyl-H4folate on mitochondrial peptide chain initiation has been studied in isolated mitochondria of Saccharomyces cerevisiae. The addition of N10-formyl-H4-folate strongly stimulates the incorporation of amino acids into mitochondrial protein at both 6 and 15 mm Mg2+. Still higher stimulation (up to 10-fold) has been obtained in the production of de novo synthesized initial...

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