Postoperative recurrences are common after resection for oesophageal cancer. From January 1986 to September 1993 31 patients (30 males, one female, mean (SD) age: 57.5 (8.8) years) were treated for locoregional recurrence (n = 24), metastases (n = 6) or both (n = 1) occurring 15.0 (12.6) months after initial surgery. Radiotherapy and chemotherapy were combined in all cases. Symptomatic improvem...

The distinguishing of intrapulmonary metastases from multiple primaries is of great clinical importance. Although comprehensive histological assessment (CHA) was recommended for addressing this problem, the limitations of CHA have been addressed. We hypothesized that a nonmucinous lepidic component with mild nuclear atypia (NLCMA) may be one of the important sign suggesting primary lesions. In ...

Ependymoma constitute 5 % to 7 % of all primary CNS neoplasm. But their prevalence relative to other tumor type varies with patient age and presenting location. Ependymoma constitute approximately 1O % of intracranial neoplasm in pediatric population and up to 30 % of those encountered in children under 3 years of age. In spinal column, ependymoma constitute 60% of glial neoplasm, and opposed...

Mucins secreted by mucus-producing cells are glycoproteins with many important functions such as antimi crobial effect, lubricity and physical barrier. The structure function of mucins may be different in various tissues. Therefore, we designed our study to reveal the current state mucin chemistry glands located partridge's esophagus. esophagus total 10 adult partridges, five female male, whose...

Bleeding is a common symptom of esophageal neoplasm; endoscopic therapy remains the initial choice of treatment. Due to too huge size, massive bleeding or intoleration of the patient, endoscopic therapy fails to control the esophageal tumor bleeding; thus, many treatment methods have been investigated. Among different treatment methods, transcatheter arterial embolization (TAE) is proven clinic...

PURPOSE To analyze the clinicopathological features and outcome of patients with pathologically proven superficial squamous cell carcinoma of the esophagus. METHODS A total of 234 consecutive cases of esophageal carcinoma in a 15-year period were reviewed. RESULTS Superficial esophageal cancer was found in five patients (2.1%). They were four men and one woman and the mean age was 52.5 year...

OBJECTIVE Given the increasing rate of obesity, the effects of excessive body weight on surgical outcomes constitute a relevant quality of care concern. Our aim was to determine the relationship between preoperative body mass index (BMI) on perioperative complications after oesophagectomy for adenocarcinoma of the oesophagus. DESIGN Retrospective database review. SETTING Single institution ...

Barrett's esophagus is the metaplastic change of the squamous epithelium lining the distal esophagus into an intestinalized columnar epithelium that predisposes to esophageal adenocarcinoma development. The cell that gives rise to Barrett's esophagus has not been identified definitively, although several sources for the Barrett's esophagus cell of origin have been postulated. One possible sourc...

Cancer-related inflammation is considered the 'seventh hallmark of cancer'; many studies show that tumours develop and progress within inflammatory diseases. This review focuses on Barrett's oesophagus, a common condition in which chronic inflammation and resulting alterations in the stroma can lead to carcinogenesis, specifically oesophageal adenocarcinoma. Changes that occur in the tissue mic...

Twelve patients with oesophageal smooth muscle tumour were operated on between 1955 and 1984 in the Department of Thoracic and Cardiovascular Surgery of Helsinki University Central Hospital. Eleven tumours were leiomyomata, the twelfth was a leiomyosarcoma. Dysphagia (83%) and chest or epigastric pains (67%) were the most common symptoms presented. All patients underwent transthoracic removal o...