BACKGROUND A 1994 National Institutes of Health consensus panel recommended that eradication of Helicobacter pylori should be first-line therapy for persons with duodenal ulcer. OBJECTIVE To assess the cost-effectiveness of H pylori eradication relative to alternative pharmacologic strategies in the long-term management of persons with confirmed duodenal ulcer. METHODS Decision analysis mod...

We model the economic incentives surrounding opium crop production in Afghanistan. Specifically, we examine the impact of eradication policies when opium is used as a means of obtaining credit, and when the crops are produced in sharecropping arrangements. The analysis suggests that when perfect credit markets are available, an increased risk of eradication will lead to less land being allocate...

A 52-year-old woman was diagnosed with cap polyposis (CP) with characteristic clinical, endoscopic, and histological features. By avoiding straining at defecation, her symptoms improved temporarily, however recrudesced. She was diagnosed with Helicobacter pylori (H. pylori) infection, and received eradication therapy successfully. After this eradication therapy, her symptoms and colonoscopic fi...

The eradication of smallpox was defined by successive WHO expert groups (WHO Scientific Group on Smallpox Eradication, 1968 ; WHO Expert Committee on Smallpox Eradication, 1972) as "the elimination of clinical illness caused by variola virus". An important corollary of this definition was that it did not involve the extinction of variola virus, as some experts had urged . The procedures for the...

Eradication of Helicobacter pylori causes improvement of gastric atrophy and intestinal metaplasia. Gastric acid secretion levels in corpus predominant gastritis increase after eradication. These changes can increase the risk of reflux esophagitis and low-dosage aspirin ulcers. Although eradication may reduce the overall risk of gastric cancer, a certain degree of risk remains, related to the e...

Objectives: Gastric cancer has been a heavy burden in Eastern Asian countries. Helicobacter pylori infection has a central role in gastric cancer development, so eradication of this infection is expected to reduce gastric cancer development. In 2012, the Japanese government decided to introduce H. pylori eradication for chronic gastritis among asymptomatic people, including having this procedur...

Although containment is frequently advocated as a fall-back option for eradication, analysis shows that it is not necessarily more economic or effective. While containment has one major advantage over eradication, in that a smaller area is managed, this must be balanced against its disadvantage; that it must continue indefinitely. Moreover, both containment and eradication programs are at risk ...

AIM To evaluate the effect of Helicobacter pylori eradication on ulcer bleeding recurrence in a prospective, long-term study including more than 400 patients. METHODS Patients with peptic ulcer bleeding were prospectively included. H. pylori infection was confirmed by rapid urease test, histology or (13)C-urea breath test. Several eradication regimens were used. Ranitidine 150 mg was administ...

Fluoroquinolones, especially levofloxacin, are used in the eradication of Helicobacter pylori worldwide. Many consensus guidelines recommend that the second-line rescue therapy for H. pylori eradication consists of a proton pump inhibitor, a quinolone, and amoxicillin as an option. Unfortunately, quinolone is well associated with a risk of developing bacterial resistance. In this paper, we revi...

Background/Aims Gastric cancers develop even after successful Helicobacter pylori eradication. We aimed to clarify the characteristics of early gastric cancers discovered after H. pylori eradication. Methods A total of 1,053 patients with early gastric cancer treated by endoscopic submucosal dissection were included. After matching the propensity score, we retrospectively investigated the cli...