The current study aimed to: a) utilize Monte Carlo simulation methods for the assessment of radiation doses imparted to all organs at risk to develop secondary radiation induced cancer, for patients undergoing radiotherapy for breast cancer; and b) evaluate the effect of breast size on dose to organs outside the irradiation field. A simulated linear accelerator model was generated. The in-field...

ntroduction:  monte  carlo  simulation  is  the  most  accurate  method  of  simulating  radiation  transport  and  predicting doses at different points of interest in radiotherapy. a great advantage of the monte carlo method  compared  to  the  deterministic  methods  is  the  ability  to  deal  accurately  with  any  complex  geometry.  its  disadvantage is the extremely long computing time r...

OBJECTIVE To compare effects of isoflurane and propofol on the cystometrogram and urethral pressure profile (UPP) in healthy female cats. ANIMALS 6 healthy female cats. PROCEDURES Cats were anesthetized, and a consistent plane of anesthesia was maintained with low and high doses of isoflurane and propofol. A 6-F double-lumen urinary catheter was placed aseptically in the urethra for cystome...

PURPOSE To determine the tolerability and pharmacokinetics of oral CI-1033, a pan-erbB tyrosine kinase inhibitor, administered over 14 consecutive days of a 21-day cycle. DESIGN Phase 1, multicenter trial involving patients with solid tumors that are refractory to standard therapy. CI-1033 was administered initially at 300 mg/day to a minimum cohort of three patients. Dose escalation proceede...

We compared reconstruction algorithms [filtered back projection (FBP), maximum likelihood expectation maximization (MLEM), and the simultaneous iterative reconstruction technique (SIRT)] in terms of the radiation dose and image quality, for exploring the possibility of decreasing the radiation dose during digital breast tomosynthesis (DBT). The three algorithms were implemented using a DBT syst...

Several investigators have pointed out that electron and neutron contamination from high-energy photon beams are clinically important. The aim of this study is to assess electron and neutron contamination production by various prostheses in a high-energy photon beam of a medical linac. A 15 MV Siemens PRIMUS linac was simulated by MCNPX Monte Carlo (MC) code and the results of percentage depth ...

background: a study has been conducted to assess two useful radiation protection indices, the annual per-capita effective dose equivalent (aed) and the genetically significant dose (gsd), from conventional diagnostic radiography in 10 counties with more than 1,886,000 inhabitants in khorasan province in iran. materials and methods: the health centre authorities of khorasan province were asked t...

background: radiation dose knowledge through xray examinations and their distribution in iran provides useful guidance on patient dose reduction. the results of the entrance skin dose (esds) of five common radiographies in all radiology centers in yazd province were reported in our previous study (2003). in the present study we have evaluated the collective effective dose of conventional x-ray ...

background: with the introduction of computed tomography in diagnostic radiology a new and fundamentally different imaging modality has become available. meanwhile, it is clear that the absorbed doses by the patients during ct were relatively high in comparison with those of other diagnostic radiology techniques. the aim of this survey was to determine the average absorbed dose in yazd province...

background: for an effective treatment planning in brachytherapy, it is necessary to know the accurate source dosimetric information such as air kerma strength, exposure rate constant, dose rate constant and redial dose distribution. the usual method to determine these factors is thermo luminescent dosimeter (tld) dosimetry. nowadays, another more accurate method is known to be the monte carlo ...