نتایج جستجو برای: cytoprotective

تعداد نتایج: 4389  

2012
Emanuela Leoncini Cecilia Prata Marco Malaguti Ilaria Marotti Antonio Segura-Carretero Pietro Catizone Giovanni Dinelli Silvana Hrelia

Among health-promoting phytochemicals in whole grains, phenolic compounds have gained attention as they have strong antioxidant properties and can protect against many degenerative diseases. Aim of this study was to profile grain phenolic extracts of one modern and five old common wheat (Triticum aestivum L.) varieties and to evaluate their potential antiproliferative or cytoprotective effect i...

Journal: :Physiological research 2014
M K Kemelo L Wojnarová N Kutinová Canová H Farghali

D-Galactosamine/Lipopolysaccharide (D-GalN/LPS) is a well known model of hepatotoxicity that closely resembles acute liver failure (ALF) seen clinically. The role of sirtuin 1 in this model has not yet been documented. However, there have been a number of studies about the cytoprotective effects of resveratrol, a SIRT1 activator, in the liver. This study was aimed at elucidating the roles of SI...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2013
Dean C Singleton Adrian L Harris

Angiogenesis inhibitors cause increased hypoxia in tumors and this results in the induction of cytoprotective autophagy. Targeting this adaptation using autophagy inhibitors can overcome resistance to antiangiogenic therapy and enhance the antitumor effects.

Journal: :Investigative Opthalmology & Visual Science 2010

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