Metastatic cancer of the umbilicus, known as Sister Mary Joseph nodule, is typically associated with visceral malignancy. It is an uncommon and rare presentation. It indicates disseminated disease and poor prognosis. Physicians need to be aware of this rare clinical condition so that they can promptly diagnose the primary cancer.

Our present study examines, in mesenteric resistance arteries, possible vasodilation alterations, and the role of NO and COX (cyclo-oxygenase) derivatives, in cirrhosis. The vasodilator response to acetylcholine was analysed in segments from control and cirrhotic rats. The effects of the non-specific COX inhibitor indomethacin, the specific COX-1 inhibitor SC-560 and the specific COX-2 inhibito...

.. Objective: To determine the frequency and severity of hypoglycemia in patients with liver cirrhosis. Study Design: Cross sectional case series study. Period: Six months. Setting: Liaquat University Hospital Hyderabad. Methods: All the patients of liver cirrhosis, of >12 years of age and of either gender were evaluated for hypoglycemia by assessing the glycemic status through random or fastin...

Cirrhotic cardiomyopathy is impaired contractile responsiveness to stress, diastolic dysfunction and electrophysiological abnormalities in the absence of known cardiac disease in cirrhotic patients. This Descriptive case series study was conducted in sree balaji medical college and hospitals. This study included 74 consecutive cases of cirrhosis of liver of either sex above 14 years of age. Fir...

Journal of the Arab Society for Medical Research 2012, 7:33–37 Background/aim An impaired lipid metabolism is often observed in patients with chronic liver diseases. This study was carried out to determine the lipid profile in cirrhotic patients with and without hepatocellular carcinoma (HCC) and to determine whether it relates to the severity of cirrhosis in Upper Egypt. Patients and methods I...

The mechanisms that mediate hyporesponsiveness to vasoconstrictors in liver cirrhosis are not completely established. In the present study we have explored the role of NO and potassium channels by studying the pressor response to methoxamine in rats with carbon tetrachloride-induced cirrhosis with ascites. Experiments were performed in the isolated and perfused mesenteric arterial bed of contro...

PURPOSE To determine the prevalence, clinical characteristics and nature of subfoveal nodules in Coats' disease and the associated impact on the long-term visual outcome. METHODS Consecutive cases of Coats' disease with foveal exudation were retrospectively reviewed. The presence of a subfoveal nodule or macular fibrosis was recorded. Clinical characteristics, retinal imaging, and outcome wer...

Despite septic arthritis is increasingly being reported in elderly patients with diabetes or alcoholism, reported cases of spontaneous bacterial arthritis in cirrhotic patients are extremely rare. We present the first reported case of K. pneumoniae septic arthritis and spontaneous bacterial peritonitis in a cirrhotic patient with hepatocellular carcinoma. K. pneumoniae, one of the most common c...

background: sonoelastography is a new ultrasound method which could be helpful to determine which thyroid nodule is malignant. we designed this study to evaluate the accuracy of sonoelastography in differentiating of benign and malignant thyroid nodules in iranian patients. methods: forty thyroid nodules in forty consecutive patients who had been referred for sonography‑guided fine‑needle aspir...

377 patients with single thyroid nodule who clinically were candidates for surgery, were selected from the patients that referred to the clinics of endocrinology at namazee hospital, shiraz medical school. fine needle aspiration (fna) was carried out without performing thyroid scan and the results were compared with histology obtained by surgery to establish its accuracy in our center. which is...