PURPOSE An improved translocation technique for autologous retinal pigment epithelium (RPE) transplantation is presented. The graft consists of a sheet of a partial-thickness choroid with RPE attached. METHODS Twenty-seven pigmented rabbits were used in this study. After mechanical debridement of Bruch membrane, partial-thickness RPE-choroid sheets were transplanted onto the subretinal space ...

Introduction. The frequency of intraocular metastases is 64–67 % all metastatic tumors eye, with the choroid being mainly affected (88–90.7 %). In majority cases, are localized in central regions fundus (in 80 between equator and macular zone) and, characterized by rapid growth symptoms increase. There practically no information literature about choroidal foloww-up during polychemotherapy. stud...

A stable intraventricular milieu is crucial for maintaining normal neuronal function. The choroid plexus epithelium produces the cerebrospinal fluid and in doing so influences the chemical composition of the interstitial fluid of the brain. Here, we review the molecular pathways involved in transport of the electrolytes Na+, K+, Cl-, and HCO3(-)across the choroid plexus epithelium.

Fourteen families with genetically determined posterior retinal dystrophies were studied by fluorescein angiography. With one exception, the families could be segregated into two clearly defined categories, one in which every member had a dark choroid, and one where each had a light choroid. This implies that the fluorescein angiography provides a means of subdividing certain of these disorders...

BACKGROUND To investigate the choroidal thickness in older patients with central serous chorioretinopathy (CSCR) compared to age-matched normal subjects. METHODS Fifteen patients (30 eyes) with CSCR, all aged ≥60 years, and 21 age-matched normal subjects (21 eyes) underwent high-definition raster scanning using SD-OCT. Both eyes from CSCR patients were included in the analysis. The eyes in pa...

Complete retinal regeneration in adult animals occurs only in certain urodele amphibians, in which the retinal pigmented epithelial cells (RPE) undergo transdifferentiation to produce all cell types constituting the neural retina. A similar mechanism also appears to be involved in retinal regeneration in the embryonic stage of some other species, but the nature of this mechanism has not yet bee...

Brain homeostasis depends on the composition of both brain interstitial fluid and CSF. Whereas the former is largely controlled by the blood-brain barrier, the latter is regulated by a highly specialized blood-CSF interface, the choroid plexus epithelium, which acts either by controlling the influx of blood-borne compounds, or by clearing deleterious molecules and metabolites from CSF. To inves...

Well-known as one of the main sources of cerebrospinal fluid (CSF), the choroid plexuses have been, and still remain, a relatively understudied tissue in neuroscience. The choroid plexus and CSF (along with the blood-brain barrier proper) are recognized to provide a robust protective effort for the brain: a physical barrier to impede entrance of toxic metabolites to the brain; a "biochemical" b...

In 1948 two of us (Illingworth and Wright) reviewed the literature conceming tubercles of the choroid and described the natural history of the disease as seen in children under our care. We pointed out that the favourable response of children with miliary or meningeal tuberculosis to streptomycin treatment had for the first time made possible the study of the natural history of choroidal tuberc...