background: diazinon is a widely used organophosphate insecticide which is applied against plant pests. this compound has various side effects because it acts as an acetyl cholinesterase enzyme inhibitor. objective: the aim of present study was to investigate the effects of diazinon on pituitary–gonad axis and ovarian histological changes in rats. materials and methods: in total 50 female wista...

The in vitro effect of procainamide on plasma cholinesterase (PCHE) activity in the plasma of ten normal ASA physical status I patients was studied using a kinetic method. The mean plasma cholinesterase activity without procainamide (control) was 0.90 +/- 0.09 units.ml-1. The dibucaine numbers of all the samples were in the normal range of 78 to 86, indicating normal genotypes. The mean plasma ...

Plasma pseudocholinesterase has no known physiological role but is essential for the rapid degradation of succinyicholine, a muscle relaxant used in surgical procedures. Depression of effective enzyme concentrations as a result of hepatocellular disease or exposure to anticholinesterase agents will increase the patient’s sensitivity to succinyicholine and prolong postoperative apnea. Synthesis ...

BACKGROUND Farmworkers can be exposed to a wide variety of pesticides. Assessing cholinesterase activity over time can be used to monitor exposure to organophosphorus and carbamate pesticides. OBJECTIVES The goal of this study was to document patterns and variation in cholinesterase levels across the agricultural season (May-August) among field-workers, and to explore the association of choli...

STUDY OBJECTIVE To evaluate the usefulness of two new parameters for separating pleural transudates and exudates: pleural fluid cholinesterase level and pleural fluid to serum cholinesterase ratio, and to compare the results with the other well-established criteria. DESIGN Prospective evaluation of the patients referred for diagnostic thoracentesis. SETTING Pulmonary sections of a community...

Phytochemicals found in extracts obtained from plants are very important bioactive constituents. In this study, phytochemicals extract content Celtis tournefortii .Lam. tree (CT) leaves were determined by a LC-MS method. The constituents with the major concentrations was rutin (2479.89 µg ml-1), coumarin (1241.68 biochanin A (1026.42 shikimic acid (477.32 chlorogenic (300.76 ml-1). suppressive ...

Fifteen patients demonstrating unexpected prolonged apnoea lasting several hours after succinylcholine have been treated by a new preparation of human serum cholinesterase. Adequate spontaneous respiration was re-established in an average period of ten minutes after the injection. In 12 patients biochemical genetic examinations confirmed the presence of an atypical serum cholinesterase. In thre...

Alzheimer's Disease (AD), one of the diseases that still has no a specific therapy, become major public health issue owing to increasing population elderly, particularly in rich countries. Inhibitory cholinesterase enzymes (acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), which hydrolyze acetylcholine (ACh) butyrylcholine (BCh) neurotransmitters, have recently choice for therapy th...