نتایج جستجو برای: cell lymphocytosis

تعداد نتایج: 1685334  

Journal: :The European respiratory journal 1989
M A Johnson A Nemeth A Condez S W Clarke L W Poulter

Eighteen precipitin-positive pigeon breeders, thirteen symptomatic (SPB), with extrinsic allergic alveolitis (EAA), and five asymptomatic (APB), without lung disease, underwent bronchoalveolar lavage (BAL). Cytospins were prepared on which differential cell counts were performed. Immunocytological methods, using monoclonal antibodies, were performed to identify lymphocyte and macrophage subsets...

Journal: :Blood 2011
Julia Hoellenriegel Sarah A Meadows Mariela Sivina William G Wierda Hagop Kantarjian Michael J Keating Neill Giese Susan O'Brien Albert Yu Langdon L Miller Brian J Lannutti Jan A Burger

In lymphocytes, the phosphoinositide 3'-kinase (PI3K) isoform p110δ (PI3Kδ) transmits signals from surface receptors, including the B-cell receptor (BCR). CAL-101, a selective inhibitor of PI3Kδ, displays clinical activity in CLL, causing rapid lymph node shrinkage and a transient lymphocytosis. Inhibition of pro-survival pathways, the presumed mechanism of CAL-101, does not explain this charac...

Journal: :Journal of clinical pathology 1994
M Lima J Coutinho A Orfão A L Macedo J F San Miguel B Justiça

A case of a 58 year old woman with a chronic lymphoproliferative disorder of unusual clinical presentation, disease course, and immunophenotype is presented. At diagnosis she had severe anaemia, moderate lymphocytosis with some cells having prolymphocytoid features and a normal platelet count. A clinical examination yielded negative results. Only anaemia related symptoms were found and the pati...

2011
Shrinivas Bishu Violeta Arsenescu Eun Y Lee H David Vargas Willem JS de Villiers Razvan Arsenescu

BACKGROUND Adult onset autoimmune enteropathy (AIE) is a rare condition characterized by diarrhea refractory to dietary therapy diagnosed in patients with evidence of autoimmune conditions. Auto-antibodies to gut epithelial cells and other tissues are commonly demonstrated. Despite increasing awareness, the pathogenesis, histologic, immunologic and clinical features of AIE remain uncertain. The...

Journal: :British journal of haematology 2007
Ola Landgren Robert A Kyle

Multiple myeloma and chronic lymphocytic leukaemia share common biological and clinical features including the presence of defined precursor conditions (monoclonal gammopathy of undetermined significance and monoclonal B-cell lymphocytosis respectively). Here, we discuss evidence from the literature on the potential aetiological roles for genetic and chronic immune stimulatory factors on the pa...

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