In this syudy a continuous bovine kidney cell line derived from a primary bovine kidney cells was established for the first time in Iran. The cells were originating from two-day-old normal male calf of Holstein breed. The cell cultures were continuously passaged following complete proliferation of primary cells. The specific properties or characteristics of the cell were defined using cytogenet...

Decreased expression of E-cadherin correlates with poor prognosis in colorectal cancer. Certain E-cadherin signaling cascades are triggered by intercellular force or binding to cadherins on adjacent cells. Three-dimensional (3D) cell cultures represent a better approximation of cell-cell adhesion in vivo than two-dimensional (2D) cultures. Here, we explored the role of E-cadherin in colorectal ...

Abstract Comparative single-cell studies of group 3/4 medulloblastomas (MBs) and fetal brain have identified a common hierarchy glutamatergic-lineage cell types an apparent cell-of-origin in the rhombic lip. An increased understanding genetic regulators stem-cell maintenance differentiation MB would clearly be therapeutic benefit. There is significant need for lineage-tracing systems to model m...

Drug-induced liver injury (DILI) is the reason for 15–18% of medicinal product recalls from market. Since interspecies differences often limit relevance standard non-clinical tests in vivo , a promising alternative to develop cell-based vitro methods. The aim study was review current advances cell modelling identification DILI. In mechanistic studies DILI require cells that exhibit activity spe...

Objective: Microbiological infection plays vital role in determining the outcome as well as cost and duration of the hospital stay for patients admitted in ICU setup. Therefore regular surveillance of important pathogens and its related factors are mandatory. The objective of this study was to find out the organisms causes infection in patients admitted in different Trauma-surgery, medical and ...