abstract background and purpose: distress is an important issue with significant effects on nurses and patients in the nursing profession. this study aimed to investigate the effects of mindfulness-based cognitive therapy (mbct) on the distress tolerance of nurses with job burnout. methods: this quasi-experimental study was conducted with a pretest-posttest design and a control group. study pop...

objectives : this study aimed to investigate the long-term effects of mindfulness-based therapy on improving life quality of patients with irritable bowel syndrome. method : this was an experimental study including 24 patients (12 from each group) with ibs syndrome were selected based on the romeiii criteria and were randomly placed in the test and control groups. in both groups, the scales of ...

objectives: this study aimed at investigating the effectiveness of mindfulness based cognitive therapy (mbct) in management of pain and functional limits of chronic pain patients. methods & materials: in this semi-experimental study, 30 volunteer female patients suffering from chronic pain attending a clinical assessment for treatment of chronic pain were recruited using the convenience samplin...

stem cells are cells with the ability to divide for indefinite periods and to give rise to specialized cells.  stem cell therapy has now been emerged as an extraordinary promise to treat a wide range of diseases and conditions.  however, except blood stem cell transfer by bone marrow transplant which has been used as an standard practice for more than 50 years, nearly all of therapeutic potenti...

Introduction: In this study, we explore in detail cell-specific targeting efficacy of nano-photo-thermal therapy (NPTT) method and the resulting responses that are induced by variable laser intensities and exposure times in cancer cells to induce selective apoptosis. We delineate the synthesis of a high-yielding synthetic F-AuNPs by tailoring the surface of gold nanoparticles ...

Neurodegenerative diseases are the hereditary and sporadic diseases which are characterized by progressive neuronal loss of the nervous system and are emerging as the leading cause of death, disabilities, and a socioeconomic burden due to an increase in life expectancy. There are many neurodegenerative diseases including Alzheimer’s disease, Parkinson’s, disease, amyotrophic lateral...

Objective(s): Development of molecules that specifically recognize cancer cells is one of the major areas in cancer research. Human epidermal growth factor receptor 2 (HER2) is specifically expressed on the surface of breast cancer cells. HER2 is associated with an aggressive phenotype and poor prognosis. In this study we aimed to isolate RNA aptamers that specifically bind to HER2 overexpressi...

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background: cell therapy of many neurodegenerative diseases using bone marrow stromal cells (bmsc) requires the differentiation of bmsc into neuronal subtype. however, the transdifferentiation of bmsc into gabaergic phenotype requires more investigation. methods: in this study, bmsc of adult female rats were pre-induced into neuroblast-like cells using 1 mm β-mercaptoethanol (βme) and 10 m ret...

background: special care needs of mentally retarded children can affect the mental health of the mother. the purpose of this study was the efficacy of mindfulness-based cognitive therapy (mbct) on reducing depression and increasing life expectancy of mothers with mentally retarded children. methods: this study was a two group quasi-experimental plan with pre and post test. the population has fo...