BACKGROUND Obsessive-compulsive disorder (OCD) is a very disabling condition with a chronic course, if left untreated. Though cognitive behavioral treatment (CBT) with or without selective serotonin reuptake inhibitors (SSRI) is the method of choice, up to one third of individuals with obsessive-compulsive disorder (OCD) do not respond to treatment in terms of at least 35% improvement of sympto...

objective: obsessive-compulsive disorder (ocd) is one of the greatest and debilitating disorders, which many of its patients do not respond to psychotherapy and pharmacotherapy. in this regard, paying attention to new treatments such as transcranial direct current stimulation (tdcs) is important. the purpose of the present research was to examine the effects of tdcs on the obsession-compulsion ...

most obsessive-compulsive disorder (ocd) patients meet psychiatrists 5 to 10 years after onset of ocd .its relatively high prevalence ratio and the delay in seeking help suggest that patients with ocd may seek help at non-psychiatric clinics. the present study was undertaken to provide some epidemiological data on the prevalence and severity of ocd in dermatological patients. the participants i...

BACKGROUND Selective serotonin reuptake inhibitors (SSRIs) and exposure with response prevention for treatment of obsessive-compulsive disorder (OCD) have demonstrated empirical support; however, a substantial number of patients remain with clinically significant OCD symptoms after such treatments. OBJECTIVES The aim of this study was to compare the effectiveness of acceptance and commitment ...

OBJECTIVE Because of the irreversibility of lesioning procedures and their possible side effects, we studied the efficacy of replacing bilateral anterior capsulotomy with chronic electrical capsular stimulation in patients with severe, long-standing, treatment-resistant obsessive-compulsive disorder. METHODS We stereotactically implanted quadripolar electrodes in both anterior limbs of the in...

BACKGROUND Purpose of this study is comparing early maladaptive schemas which are active in patients suffering from obsessive-compulsive disorder and anxiety disorders together, considering recent DSM-5 changes through which OCD has been placed in a separate and new diagnostic level. METHODOLOGY This research is a causal-comparative study. 151 persons were categorized in three groups of peopl...

OBJECTIVE In many patients with obsessive-compulsive disorder (OCD), residual symptoms persist despite a clinically meaningful response. The objective of this study was to examine whether addition of behavior therapy would augment treatment outcome in these patients. METHOD Ninety-six patients with DSM-IV OCD who had responded to 3 months of drug treatment were randomly assigned to either rec...

Background and Objectives: Cognitive models suggest that attentional biases are integral in the maintenance of obsessive-compulsive symptoms (OCS). Such biases have been established experimentally in anxiety disorders; however, the evidence is unclear in Obsessive Compulsive disorder (OCD). In the present study, an eye-tracking methodology was employed to explore attentional biases in relation ...

BACKGROUND The drug treatments of choice for obsessive-compulsive disorder (OCD) are serotonin reuptake inhibitors (SRIs). However, a correlation between the neuropeptide oxytocin in cerebrospinal fluid and the severity of OCD has previously been shown, and oxytocin and serotonin are interconnected within the brain. Few studies have investigated whether SRIs have any effect on oxytocin; thus, o...