نتایج جستجو برای: brain effect
تعداد نتایج: 2056104 فیلتر نتایج به سال:
objective(s) several lines of evidence indicate that neuropeptides exhibit protective properties against gastroduodenal ulcers. neurotensin, a gut-brain neuropeptide, is implicated in a number of physiological processes in the central nervous system and peripheral tissues including gastrointestinal tract. in the present study, we aimed to investigate the gastroprotective potential of either per...
introduction: voxel based morphometry is a type of statistical parametric mapping that can be used to investigate the effect of diseases such as epilepsy, alzheimer's disease and parkinson's disease or other agent such as skills on brain structure (white matter, gray matter and cerebrospinal fluid). the aim of this study is evaluate the effectiveness of this method in detection of dif...
Objective: Gut–brain axis (GBA) is very important in creation and modulation of gastrointestinal problems. Aloe vera gel has gastroprotective properties. The purpose of this study was to evaluate the effect of aqueous extract of Aloe vera leaves on the gastric acid secretion and brain and intestinal water content following acetic acid gastric ulcer induction. Materials and Methods: Gastric ulce...
One of the newest methods to reduce cerebral ischemia damages is cell therapy. The aim of this study is to evaluate the effect of Sertoli cell transplantation on ischemia-induced injuries in animal models of stroke. Rats were divided into four groups: transplant+ischemia, ischemia, sham, and control. Sertoli cells were separated from the other testis of rats and cultured. Unilateral Sertoli cel...
Background: We earlier reported that datumetine possesses binding affinity with NMDAR and that 14-day exposure to datumetine altered NMDAR signalling by mimicking glutamate toxicity. Here, we investigated the potential neuroprotective effect of a single shot of a low dose of datumetine administration in BALB/c mice. Results: Relative to Veh, datumetine downregulate the expression of CamKIIα i...
Background and Objectives: In the early stages of brain ischemia, the production of free radicals increases. Salvia officinalis is a rich source of antioxidant compounds. Therefore, in this study the effects of hydroalcoholic extract of Salvia officinalis on blood -brain barrier permeability and neurological deficits have been studied. Materials and Methods: In this experimental study 35 m...
Background: Early diagnosis of brain tumors has significant effect on the treatment process. Brain metastatic tumors are usually diagnosed following the neurological symptoms in patients or incidentally after Computerized Tomography (CT) scan and Magnetic Resonance Imaging (MRI) requests of the brain. Objectives: Implementation of a new method for being informed about the origin of brain tumors...
Neurodegenerative diseases (NDs) have become a serious global health problem as the population ages. Traditionally, treatment strategies for NDs included oral and intravenous administration; however, blood–brain barrier (BBB) can prevent drugs from reaching brain, rendering incomplete effect unsatisfactory. Additionally, prolonged or excessive use of that cross BBB damage liver kidney function....
Serotonin is believed as an important factor in brain function. The role of serotonin in cerebral psycho-patho-physiology has already been well established. However, the function of serotonin antagonist in anesthetized subjects under hyperthermia has not been studied properly. Methods: Experiments were performed in three groups of urethane-anesthetized rats, such as: (i) control group, (ii) wh...
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