I report two patients undergoing open heart surgery, with nitrous oxide and isoflurane anaesthesia, for whom bispectral index (BIS) monitoring showed high BIS values with nitrous oxide and isoflurane anaesthesia. The BIS decreased immediately after nitrous oxide was stopped and increased again after nitrous oxide was restarted.

Background. Millions of children with neurological diseases are subjected to general anesthesia every year. The conditions under which surgeries done in these patients depend on a number interrelated factors that arise deficiency and often the cause anesthetic complications. possibility using monitoring bispectral index pediatric disorders is particular interest, specifically those hydrocephalu...

recent developments and anesthetic implications. Anesthesiology 1996; 84: 173–89 2 Lydic R, Baghdoyan HA. Cholinergic contributions to the control of consciousness, anesthesia. In: Yaksh TL, Lynch C III, Zapole WM, Maze M, Biebuyck JF, Saidman LJ, eds. Biologic Foundations. Philadelphia: Lippincott-Raven, 1997; 433–50 3 Meuret P, Backman SB, Bonhomme V, Plourde G, Fiset P. Physostigmine reverse...

BACKGROUNDS Parturients are thought to be more sensitive to inhalational anesthetics because their minimum alveolar concentration is decreased. However, this conventional theory may be wrong, because, according to recent animal studies, minimum alveolar concentration indicates anesthetic effect on the spinal cord but not on the brain. The aim of this electroencephalographic study was to investi...

BACKGROUND To support safe and effective use of propofol in nonventilated children after major surgery, a model for propofol pharmacokinetics and pharmacodynamics is described. METHODS After craniofacial surgery, 22 of the 44 evaluated infants (aged 3-17 months) in the pediatric intensive care unit received propofol (2-4 mg . kg-1 . h-1) during a median of 12.5 h, based on the COMFORT-Behavio...

Abbreviations TIVA, Total intravenous anesthesia; TCI, target-controlled infusion; BIS, Bispectral Index; EDM, Esophageal ultrasonography monitoring; TBRI, Theodor Bilharz Research Institute; ASA, American society of anesthesiologists; MBP, mean blood p HR, heart rate; BMI, body mass index; Ce, effect site concentration; TOF, train of four; Ftc, flow time corrected; PV, peak velocity; SD distan...